IpiRecord: IPI00013404

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytoplasm	C	IEA	IEA	ISS IDA
intracellular	C	IEA	IEA	IEA
nucleus	C	TAS	IDA IDA	ISS ISS IDA IEA
transcription factor complex	C	IPI	IPI	ISS IEA
protein complex	C			IDA
DNA binding	F		IDA IDA	ISS IDA
transcription cofactor activity	F	TAS		ISS
transcription factor activity	F	TAS	IDA IDA IDA	ISS ISS IEA
transcription activator activity	F	IEA	IDA	ISS IEA
protein binding	F	IPI IPI	IPI IPI IPI	ISS ISS IDA IPI IEA
SMAD binding	F			IPI
ureteric bud branching	P	IEA	IGI	ISS IEA
SMAD protein nuclear translocation	P		IEA
kidney development	P	IEA	IMP	IEA
negative regulation of cell proliferation	P	IEA	IGI	ISS IEA
gastrulation (sensu Mammalia)	P	IEA	IMP	ISS IEA
transcription	P	IEA	IEA	IEA
regulation of binding	P	IEA	IDA	ISS IEA
regulation of transcription from RNA polymerase II promoter	P		IDA	ISS
SMAD protein complex assembly	P	TAS		ISS
positive regulation of transcription, DNA-dependent	P		IDA	ISS
positive regulation of transcription from RNA polymerase II promoter	P	IEA	IDA IDA	ISS IEA
regulation of transcription, DNA-dependent	P	IEA	IEA IEA
common-partner SMAD protein phosphorylation	P		IEA
anterior/posterior pattern formation	P	IEA	IMP	ISS IEA
organ morphogenesis	P		IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (18)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un Un
cellular phenotype	MP		Un
behavior/neurological phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un Un
homeostasis/metabolism phenotype	MP		Un
embryogenesis phenotype	MP		Un Un Un Un Un
lethality-embryonic/perinatal	MP		Un Un Un Un Un Un
lethality-postnatal	MP		Un
renal/urinary system phenotype	MP		Un
nervous system phenotype	MP		Un Un
tumorigenesis	MP		Un Un Un Un Un
cardiovascular system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un Un
normal phenotype	MP		Un Un
hematopoietic system phenotype	MP		Un
reproductive system phenotype	MP		Un
life span-post-weaning/aging	MP		Un Un Un
growth/size phenotype	MP		Un Un Un

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Adenomatous Polyposis Coli	D			ISSISS
Colorectal Neoplasms, Hereditary Nonpolyposis	D			ISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
SMAD dependent signaling pathways	W			IDA
transforming growth factor-beta signaling pathway - SMAD dependent	W			IDA

KEGG Pathway (7)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
TGF-beta signaling pathway (04350)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cell cycle (04110)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Adherens junction (04520)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Wnt signaling pathway (04310)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway