IPI report for IPI00013452

IpiRecord: IPI00013452

IPI00013452 - EPRS, GLUTAMYL-PROLYL TRNA SYNTHETASE.
Uniprot Accession: Q86X73
Uniprot ID: Q86X73_HUMAN
Mapping: Chr 1, 218208566 - 218286623
Entrez Gene: 2058
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P07814 UniProtKB/Swiss-Prot: SYEP_HUMAN Vega: OTTHUMP00000035562 REFSEQ_REVIEWED: NP_004437 REFSEQ_REVIEWED: GI:62241042 UniProtKB/TrEMBL: A0AVA9 UniProtKB/TrEMBL: A0AVA9_HUMAN UniProtKB/TrEMBL: Q05BP6 UniProtKB/TrEMBL: Q05BP6_HUMAN UniProtKB/TrEMBL: Q05DF8 UniProtKB/TrEMBL: Q05DF8_HUMAN UniProtKB/TrEMBL: Q3KQZ8 UniProtKB/TrEMBL: Q3KQZ8_HUMAN UniProtKB/TrEMBL: Q5DSM1 UniProtKB/TrEMBL: Q5DSM1_HUMAN UniProtKB/TrEMBL: Q5H9S5 UniProtKB/TrEMBL: Q5H9S5_HUMAN UniProtKB/TrEMBL: Q6PD57 UniProtKB/TrEMBL: Q6PD57_HUMAN UniProtKB/TrEMBL: Q86X73 UniProtKB/TrEMBL: Q86X73_HUMAN ENSEMBL: ENSP00000355890 ENSEMBL: ENSG00000136628 H-InvDB: HIT000321887 UniParc: UPI0000205E8C HGNC: 3418 Entrez Gene: 2058 UniGene: Hs.497788 CCDS: CCDS31027.1 trome: HTR006067 UTRdb: BB005480 UTRdb: BB286683 UTRdb: BB384745 UTRdb: BB394682 RZPD: Hs.497788 CleanEx: HS_EPRS CleanEx: HS_QARS InterPro: IPR002314 InterPro: IPR001412 InterPro: IPR006195 InterPro: IPR004154 InterPro: IPR004526 InterPro: IPR000924 InterPro: IPR010987 InterPro: IPR015263 InterPro: IPR002316 InterPro: IPR004499 InterPro: IPR011035 InterPro: IPR014729 InterPro: IPR009068 InterPro: IPR000738 Pfam: PF03129 Pfam: PF09180 Pfam: PF00749 Pfam: PF03950 Pfam: PF00587 Pfam: PF00458 PRINTS: PR00987 PRINTS: PR01046 TIGRFAMs: TIGR00463 TIGRFAMs: TIGR00408 PROSITE: PS00178 PROSITE: PS50862 PROSITE: PS00762 PROSITE: PS51185 SUPERFAMILY: SSF52954 SUPERFAMILY: SSF47616 SUPERFAMILY: SSF50715 SUPERFAMILY: SSF47060 PANTHER: PTHR10119 GENE3D: G3DSA:1.10.287.10 GENE3D: G3DSA:3.40.50.620 GENE3D: G3DSA:3.40.50.800

IPI00013452 - EPRS, GLUTAMYL-PROLYL TRNA SYNTHETASE.

Uniprot Accession: Q86X73

Uniprot ID: Q86X73_HUMAN

Mapping: Chr 1, 218208566 - 218286623

Entrez Gene: 2058

Entrez MapView: Geneprod

+All IPI Database Cross References

UniProtKB/Swiss-Prot: P07814
UniProtKB/Swiss-Prot: SYEP_HUMAN
Vega: OTTHUMP00000035562
REFSEQ_REVIEWED: NP_004437
REFSEQ_REVIEWED: GI:62241042
UniProtKB/TrEMBL: A0AVA9
UniProtKB/TrEMBL: A0AVA9_HUMAN
UniProtKB/TrEMBL: Q05BP6
UniProtKB/TrEMBL: Q05BP6_HUMAN
UniProtKB/TrEMBL: Q05DF8
UniProtKB/TrEMBL: Q05DF8_HUMAN
UniProtKB/TrEMBL: Q3KQZ8
UniProtKB/TrEMBL: Q3KQZ8_HUMAN
UniProtKB/TrEMBL: Q5DSM1
UniProtKB/TrEMBL: Q5DSM1_HUMAN
UniProtKB/TrEMBL: Q5H9S5
UniProtKB/TrEMBL: Q5H9S5_HUMAN
UniProtKB/TrEMBL: Q6PD57
UniProtKB/TrEMBL: Q6PD57_HUMAN
UniProtKB/TrEMBL: Q86X73
UniProtKB/TrEMBL: Q86X73_HUMAN
ENSEMBL: ENSP00000355890
ENSEMBL: ENSG00000136628
H-InvDB: HIT000321887
UniParc: UPI0000205E8C
HGNC: 3418
Entrez Gene: 2058
UniGene: Hs.497788
CCDS: CCDS31027.1
trome: HTR006067
UTRdb: BB005480
UTRdb: BB286683
UTRdb: BB384745
UTRdb: BB394682
RZPD: Hs.497788
CleanEx: HS_EPRS
CleanEx: HS_QARS
InterPro: IPR002314
InterPro: IPR001412
InterPro: IPR006195
InterPro: IPR004154
InterPro: IPR004526
InterPro: IPR000924
InterPro: IPR010987
InterPro: IPR015263
InterPro: IPR002316
InterPro: IPR004499
InterPro: IPR011035
InterPro: IPR014729
InterPro: IPR009068
InterPro: IPR000738
Pfam: PF03129
Pfam: PF09180
Pfam: PF00749
Pfam: PF03950
Pfam: PF00587
Pfam: PF00458
PRINTS: PR00987
PRINTS: PR01046
TIGRFAMs: TIGR00463
TIGRFAMs: TIGR00408
PROSITE: PS00178
PROSITE: PS50862
PROSITE: PS00762
PROSITE: PS51185
SUPERFAMILY: SSF52954
SUPERFAMILY: SSF47616
SUPERFAMILY: SSF50715
SUPERFAMILY: SSF47060
PANTHER: PTHR10119
GENE3D: G3DSA:1.10.287.10
GENE3D: G3DSA:3.40.50.620
GENE3D: G3DSA:3.40.50.800

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11575)
Rat: Eprs, 170 KDA PROTEIN.
Mouse: Eprs, BIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE.
Rat: Eprs, LRRGT00050.
Human: EPRS, GLUTAMYL-PROLYL TRNA SYNTHETASE.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11575)

Rat: Eprs, 170 KDA PROTEIN.

Mouse: Eprs, BIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE.

Rat: Eprs, LRRGT00050.

Human: EPRS, GLUTAMYL-PROLYL TRNA SYNTHETASE.

Annotations for EPRS and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytoplasm	C	TAS	IEA	IEA ISS
soluble fraction	C	TAS		ISS
glutamate-tRNA ligase activity	F	IEA	IEA IEA	IEA
ATP binding	F	IEA	RCA	IEA ISS
nucleotide binding	F	IEA	IEA IEA
protein binding	F	IPI
aminoacyl-tRNA ligase activity	F		RCA	ISS
catalytic activity	F		IEA
ligase activity	F	IEA	IEA
proline-tRNA ligase activity	F	IEA	IEA IEA	IEA
actin binding	F		RCA	ISS
glutamyl-tRNA aminoacylation	P	IEA	IEA	IEA
protein complex assembly	P	TAS		ISS
tRNA aminoacylation for protein translation	P		RCA	ISS
translation	P		IEA IEA
prolyl-tRNA aminoacylation	P	IEA	IEA	IEA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Porphyrin and chlorophyll metabolism (00860)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Glutamate metabolism (00251)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Arginine and proline metabolism (00330)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Aminoacyl-tRNA biosynthesis (00970)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway