IpiRecord: IPI00013508

IPI00013508 - ACTN1, ALPHA-ACTININ-1.
Uniprot Accession: Q86TX4
Uniprot ID: Q86TX4_HUMAN
Mapping: Chr 14, 68410793 - 68515747
Entrez Gene: 87
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6352)
Rat: Actn1, ALPHA-ACTININ-1.
Mouse: Actn1, ALPHA-ACTININ-1.
Rat: Actn1, BRAIN-SPECIFIC ALPHA ACTININ 1 ISOFORM.
Human: ACTN1, ALPHA-ACTININ-1.
Human: ACTN1, ACTININ ALPHA 1 ISOFORM B.
Human: ACTN1, 11 KDA PROTEIN.
Human: ACTN1, 14 KDA PROTEIN.

Annotations for ACTN1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
actin cytoskeletonCISS 
cortical cytoskeletonCTAS 
stress fiberCTAS 
secretory granuleCNAS 
cytoplasmCIEA IEA IDA 
focal adhesionCIMP TAS ISS 
dense core granule membraneCTAS 
Z discCIEA IDA ISS 
pseudopodiumCTAS ISS 
cytoskeletonCIEA IEA IEA 
dendritic spineCIDA 
integrin bindingFIDA ISS 
calcium ion bindingFIEA RCA ISS IEA 
vinculin bindingFIPI ISS 
protein bindingFIPI IPI IPI ISS ISS 
protein homodimerization activityFTAS 
actin filament bindingFIEA IDA ISS 
actin bindingFIEA ISS IEA 
negative regulation of cell motilityPIMP ISS 
regulation of apoptosisPNAS ISS 
actin filament bundle formationPIEA IDA 
biological_processPND 
focal adhesion formationPIMP ISS 
cortical cytoskeleton organization and biogenesisPTAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway