| IPI00013773 - RIPK1, RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 1. | |
|---|---|
| Uniprot Accession: Q59H33 | |
| Uniprot ID: Q59H33_HUMAN | |
| Mapping: Chr 6, 3009212 - 3060418 | |
| Entrez Gene: 8737 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13207) |
|---|
| Rat: Ripk1_predicted, SIMILAR TO RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2. |
| Mouse: Ripk1, RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 1. |
| Human: RIPK1, RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IEA | IEA | |
| ATP binding | F | IEA | IEA IEA | |
| kinase activity | F | IEA | ||
| protein binding | F | IPI | IPI | ISS |
| signal transducer activity | F | IEP | ISS | |
| protein serine/threonine kinase activity | F | TAS | IEA IEA | ISS |
| protein-tyrosine kinase activity | F | IEA | IEA | ISS |
| protein kinase activity | F | ISS | ||
| nucleotide binding | F | IEA | IEA | |
| transferase activity | F | IEA | IEA | |
| apoptosis | P | TAS | IEA | ISS |
| positive regulation of I-kappaB kinase/NF-kappaB cascade | P | IEP | ISS | |
| protein amino acid phosphorylation | P | IEA | IEA | |
| signal transduction | P | TAS | IEA | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| adipose tissue phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| hematopoietic system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Toll-like receptor signaling pathway (04620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |