IPI report for IPI00014068

IpiRecord: IPI00014068

IPI00014068 - PAK4, ISOFORM 1 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.
Uniprot Accession: O96013-1
Uniprot ID: PAK4_HUMAN
Mapping: Chr 19, 44308260 - 44361886
Entrez Gene: 10298
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: O96013-1 UniProtKB/Swiss-Prot: PAK4_HUMAN Vega: OTTHUMP00000068326 Vega: OTTHUMP00000077775 Vega: OTTHUMP00000077776 Vega: OTTHUMP00000077777 REFSEQ_REVIEWED: NP_001014831 REFSEQ_REVIEWED: GI:62422554 REFSEQ_REVIEWED: NP_001014832 REFSEQ_REVIEWED: GI:62422557 REFSEQ_REVIEWED: NP_005875 REFSEQ_REVIEWED: GI:5031975 ENSEMBL: ENSP00000351049 ENSEMBL: ENSG00000130669 H-InvDB: HIT000039881 UniParc: UPI0000001281 HGNC: 16059 Entrez Gene: 10298 UniGene: Hs.20447 CCDS: CCDS12528.1 EPD: EP74132 UTRdb: BB201542 UTRdb: BB284199 UTRdb: BB387870 UTRdb: BB390304 UTRdb: BB392488 RZPD: Hs.20447 InterPro: IPR011009 InterPro: IPR000095 InterPro: IPR015750 InterPro: IPR000719 InterPro: IPR002290 Pfam: PF00786 Pfam: PF00069 ProDom: PD000001 SMART: SM00285 SMART: SM00220 PROSITE: PS50108 PROSITE: PS00107 PROSITE: PS50011 SUPERFAMILY: SSF56112 PANTHER: PTHR22986:SF84

IPI00014068 - PAK4, ISOFORM 1 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.

Uniprot Accession: O96013-1

Uniprot ID: PAK4_HUMAN

Mapping: Chr 19, 44308260 - 44361886

Entrez Gene: 10298

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_436)
Rat: Pak4_predicted, SIMILAR TO P21-ACTIVATED PROTEIN KINASE 4 ISOFORM 3.
Mouse: Pak4, SERINE/THREONINE-PROTEIN KINASE PAK 4.
Rat: Pak4_predicted, SIMILAR TO P21-ACTIVATED KINASE 4 ISOFORM 2 ISOFORM 2.
Rat: Pak4_predicted, SIMILAR TO P21-ACTIVATED KINASE 4 ISOFORM 3 ISOFORM 1.
Human: PAK4, ISOFORM 1 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.
Human: PAK4, ISOFORM 2 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.
Human: PAK4, ISOFORM 4 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.
Human: PAK4, ISOFORM 3 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_436)

Rat: Pak4_predicted, SIMILAR TO P21-ACTIVATED PROTEIN KINASE 4 ISOFORM 3.

Mouse: Pak4, SERINE/THREONINE-PROTEIN KINASE PAK 4.

Rat: Pak4_predicted, SIMILAR TO P21-ACTIVATED KINASE 4 ISOFORM 2 ISOFORM 2.

Rat: Pak4_predicted, SIMILAR TO P21-ACTIVATED KINASE 4 ISOFORM 3 ISOFORM 1.

Human: PAK4, ISOFORM 1 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.

Human: PAK4, ISOFORM 2 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.

Human: PAK4, ISOFORM 4 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.

Human: PAK4, ISOFORM 3 OF SERINE/THREONINE-PROTEIN KINASE PAK 4.

Annotations for PAK4 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Mouse	Rat
Golgi apparatus	C	RCA	ISS ISS
protein-tyrosine kinase activity	F		ISS
ATP binding	F	RCA	ISS IEA
protein serine/threonine kinase activity	F	RCA	ISS IEA
kinase activity	F	IEA
transferase activity	F	RCA	ISS
nucleotide binding	F	IEA
protein kinase activity	F	RCA	ISS
protein amino acid phosphorylation	P	RCA	ISS IEA
cell morphogenesis	P	RCA	ISS
cell motility	P	RCA	ISS ISS
signal transduction	P	RCA	ISS ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Mouse
lethality-embryonic/perinatal	MP	Un
muscle phenotype	MP	Un
nervous system phenotype	MP	Un
cardiovascular system phenotype	MP	Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Axon guidance (04360)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway