IpiRecord: IPI00016027

IPI00016027 - FZD2, FRIZZLED-2 PRECURSOR.
Uniprot Accession: Q86UZ8
Uniprot ID: Q86UZ8_HUMAN
Mapping: Chr 17, 39990353 - 39992382
Entrez Gene: 2535
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10033)
Rat: Fzd2, FRIZZLED-2 PRECURSOR.
Mouse: Fzd2, FRIZZLED-2 PRECURSOR.
Human: FZD2, FRIZZLED-2 PRECURSOR.

Annotations for FZD2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS ISS 
integral to membraneCRCA TAS ISS IEA 
membraneCIEA IEA IEA IEA 
extracellular spaceCRCA ISS 
protein bindingFIEA IPI ISS IEA 
signal transducer activityFIEA 
non-G-protein coupled 7TM receptor activityFIEA IEA IEA 
receptor activityFTAS IEA ISS IEA 
G-protein coupled receptor activityFIEA IEA IEA IEA 
Wnt receptor activityFIDA 
epithelial cell differentiationPIEA IDA IGI ISS IEA 
G-protein coupled receptor protein signaling pathwayPIEA IEA IEA 
cell-cell signalingPIEA IDA ISS IEA 
establishment of tissue polarityPTAS ISS 
Wnt receptor signaling pathwayPIEA IEA IEA 
cell surface receptor linked signal transductionPIEA 
Wnt receptor signaling pathway, calcium modulating pathwayPIDA 
elevation of cytosolic calcium ion concentrationPIDA 
signal transductionPIEA 
multicellular organismal developmentPIEA IEA IEA 
G-protein signaling, coupled to cGMP nucleotide second messengerPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway