IpiRecord: IPI00016422

IPI00016422 - DCC, NETRIN RECEPTOR DCC PRECURSOR.
Uniprot Accession: Q49AK4
Uniprot ID: Q49AK4_HUMAN
Mapping: Chr 18, 48121156 - 49311021
Entrez Gene: 1630
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13728)
Rat: Dcc, DELETED IN COLORECTAL CANCER.
Mouse: Dcc, ISOFORM A OF NETRIN RECEPTOR DCC PRECURSOR.
Mouse: Dcc, ISOFORM C OF NETRIN RECEPTOR DCC PRECURSOR.
Mouse: Dcc, ISOFORM B OF NETRIN RECEPTOR DCC PRECURSOR.
Human: DCC, NETRIN RECEPTOR DCC PRECURSOR.
Human: DCC, 10 KDA PROTEIN.
Human: DCC, 18 KDA PROTEIN.
Human: DCC, 4 KDA PROTEIN.
Human: DCC, 11 KDA PROTEIN.
Human: DCC, 8 KDA PROTEIN.

Annotations for DCC and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCNR ISS 
extracellular spaceCRCA ISS 
integral to membraneCRCA ISS IEA 
membraneCIEA IEA IEA 
axonCIEA IDA IDA IMP ISS 
transmembrane receptor activityFTAS ISS 
transcription coactivator activityFIMP 
protein bindingFIPI ISS 
receptor activityFIEA 
netrin receptor activityFIMP 
axon guidancePIMP 
apoptosisPIEA IEA 
cell cyclePIEA IEA 
negative regulation of progression through cell cyclePIEA IEA 
neuron migrationPIEA IMP ISS 
axonogenesisPTAS ISS 
induction of apoptosisPTAS ISS 
multicellular organismal developmentPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn Un
lethality-embryonic/perinatalMPUn
nervous system phenotypeMPUn Un
respiratory system phenotypeMPUn
vision/eye phenotypeMPUn
tumorigenesisMPUn
pigmentation phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway