IpiRecord: IPI00016781

IPI00016781 - CD8A, ISOFORM 2 OF T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN PRECURSOR.
Uniprot Accession: P01732-2
Uniprot ID: CD8A_HUMAN
Mapping: Chr 2, 86865245 - 86871578
Entrez Gene: 925
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4662)
Rat: Cd8a, T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN PRECURSOR.
Mouse: Cd8a, T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN PRECURSOR.
Human: CD8A, ISOFORM 2 OF T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN PRECURSOR.
Human: CD8A, ISOFORM 1 OF T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN PRECURSOR.
Human: CD8A, SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN.

Annotations for CD8A and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
membraneCIEA IEA 
integral to membraneCRCA ISS IEA 
cell surfaceCIDA ISS 
external side of plasma membraneCIDA IDA IDA IDA IDA IDA IDA IDA IDA ISS IEA 
protein bindingFISS ISS 
inflammatory responsePNAS 
cell surface receptor linked signal transductionPIDA ISS IEA 
positive regulation of calcium-mediated signalingPIDA ISS IEA 
cytotoxic T cell differentiationPIMP ISS IEA 
cellular defense responsePISS 
immune responsePIEA IEA 
T cell activationPIMP 
T cell mediated immunityPIMP IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
immune system phenotypeMPUn Un Un Un Un
nervous system phenotypeMPUn
normal phenotypeMPUn
hematopoietic system phenotypeMPUn Un Un Un
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Antigen processing and presentation (04612)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway