IpiRecord: IPI00016786

IPI00016786 - CDC42, ISOFORM 2 OF CELL DIVISION CONTROL PROTEIN 42 HOMOLOG PRECURSOR.
Uniprot Accession: P60953-2
Uniprot ID: CDC42_HUMAN
Mapping: Chr 1, 22235157 - 22292024
Entrez Gene: 998
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5647)
Rat: Cdc42, ISOFORM 1 OF CELL DIVISION CONTROL PROTEIN 42 HOMOLOG PRECURSOR.
Mouse: Cdc42, ISOFORM 2 OF CELL DIVISION CONTROL PROTEIN 42 HOMOLOG PRECURSOR.
Mouse: Cdc42, ISOFORM 1 OF CELL DIVISION CONTROL PROTEIN 42 HOMOLOG PRECURSOR.
Rat: Cdc42, ISOFORM 2 OF CELL DIVISION CONTROL PROTEIN 42 HOMOLOG PRECURSOR.
Human: CDC42, ISOFORM 1 OF CELL DIVISION CONTROL PROTEIN 42 HOMOLOG PRECURSOR.
Human: CDC42, ISOFORM 2 OF CELL DIVISION CONTROL PROTEIN 42 HOMOLOG PRECURSOR.
Human: CDC42, CELL DIVISION CYCLE 42.

Annotations for CDC42 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cell projectionCIDA ISS 
intracellularCIEA IEA 
membraneCIEA 
filopodiumCRCA ISS 
nucleotide bindingFIEA IEA 
protein bindingFIPI IPI IPI IPI IPI ISS 
GTP bindingFIEA IEA IEA 
GTPase activityFTAS IDA IDA ISS RCA TAS ISS 
GTP-dependent protein bindingFIPI 
small GTPase mediated signal transductionPIEA RCA ISS 
positive regulation of phosphoinositide 3-kinase activityPIMP ISS 
establishment of cell polarityPTAS 
nuclear migrationPIMP ISS 
filopodium formationPIDA ISS 
actin filament organizationPRCA ISS 
Rho protein signal transductionPTAS ISS 
cell divisionPIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
lethality-embryonic/perinatalMPUn Un
nervous system phenotypeMPUn
vision/eye phenotypeMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Epithelial cell signaling in Helicobacter pylori infection (05120)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Pathogenic Escherichia coli infection - EHEC (05130)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pathogenic Escherichia coli infection - EPEC (05131)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway