IpiRecord: IPI00017538

IPI00017538 - ESPL1, ISOFORM 2 OF SEPARIN.
Uniprot Accession: Q14674-2
Uniprot ID: ESPL1_HUMAN
Mapping: Chr 12, 51948818 - 51973686
Entrez Gene: 9700
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7501)
Rat: Espl1_predicted, SIMILAR TO SEPARIN.
Mouse: Espl1, SEPARIN.
Rat: Espl1_predicted, SIMILAR TO SEPARIN.
Human: ESPL1, ISOFORM 2 OF SEPARIN.
Human: ESPL1, ISOFORM 1 OF SEPARIN.
Human: ESPL1, 25 KDA PROTEIN.

Annotations for ESPL1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIEA 
nucleusCIEA IEA IEA IEA 
centrosomeCISS 
hydrolase activityFIEA 
cysteine-type peptidase activityFIEA ISS 
peptidase activityFIEA IEA IEA IEA 
bindingFIEA 
protein bindingFISS 
negative regulation of sister chromatid cohesionPISS 
chromosome segregationPIEA 
homologous chromosome segregationPIMP ISS 
establishment of mitotic spindle localizationPISS 
apoptosisPISS 
meiosis IPIMP ISS 
regulation of progression through cell cyclePISS 
meiotic spindle organization and biogenesisPIMP ISS 
cytokinesisPISS 
proteolysisPIEA IEA IEA 
positive regulation of mitotic metaphase/anaphase transitionPISS 
mitotic sister chromatid segregationPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
nervous system phenotypeMPUn
normal phenotypeMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn Un
liver/biliary system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway