IpiRecord: IPI00018109

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
protein complex	C			IDA
extracellular space	C		RCA	ISS
cytoplasm	C	ISS IDA	IDA	IDA ISS ISS ISS
nucleus	C	ISS	IDA	ISS
endoplasmic reticulum	C	IEA	IEA	TAS
membrane	C	IEA	IEA	IEA
nuclear envelope	C			TAS
microsome	C	IEA	IEA
caveolar membrane	C			IDA
metal ion binding	F	IEA	IEA	IEA
heme binding	F	IEA	IEA
protein binding	F			IPI
iron ion binding	F	IEA	IEA	IEA
prostaglandin-endoperoxide synthase activity	F	NAS IEA	IEA	TAS ISS IEA
lipid binding	F			IMP
peroxidase activity	F	NAS IEA	IEA IEA	ISS IEA
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	F	IEA	IEA	IEA
oxidoreductase activity	F	IEA	IEA	IEA
cell motility	P	TAS		ISS
cyclooxygenase pathway	P	NAS		ISS
regulation of progression through cell cycle	P			IEP
response to oxidative stress	P	IEA	IEA
anagen	P	IEA	IMP	ISS IEA
negative regulation of cell proliferation	P			IDA
keratinocyte differentiation	P		NAS
fatty acid biosynthetic process	P	IEA	IEA	IEA
lipid biosynthetic process	P		IEA
blood pressure regulation	P	ISS	IMP	ISS ISS
positive regulation of cell proliferation	P			TAS
regulation of inflammatory response	P	NAS		ISS
prostaglandin biosynthetic process	P		IEA	TAS IEA
electron transport	P	IEA	IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (16)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
behavior/neurological phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un Un
homeostasis/metabolism phenotype	MP		Un Un Un Un
other phenotype	MP		Un
immune system phenotype	MP		Un Un Un
embryogenesis phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un Un Un
renal/urinary system phenotype	MP		Un Un Un Un Un
touch/vibrissae phenotype	MP		Un
respiratory system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un Un
normal phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un Un Un Un
hematopoietic system phenotype	MP		Un Un Un
reproductive system phenotype	MP		Un Un Un Un
life span-post-weaning/aging	MP		Un Un

Disease (19)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
??	B			IEP
Myocardial Infarction	D			ISS
Pulmonary Fibrosis	D			IEP
Inflammation	D			IPM
Barrett Esophagus	D			IPM
Metabolic Syndrome X	D			IEP
Seizures	D			IEP
Anaphylaxis	D			ISS
Diabetes Mellitus, Experimental	D			IEP
Osteoarthritis	D			ISS
Adenocarcinoma	D			IPM
Arteriosclerosis	D			ISSISS
Hypertension, Portal	D			IPM
Cerebrovascular Accident	D			ISS
Brain Ischemia	D			IED
Diabetic Neuropathies	D			IPM
Myocarditis	D			ISS
Reperfusion Injury	D			IED
Hypertension	D			IAGPIAGP

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
eicosanoids metabolic pathway	W			IEA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
VEGF signaling pathway (04370)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Arachidonic acid metabolism (00590)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway