IpiRecord: IPI00018695

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C			IDA
extracellular region	C	TAS IEA	IEA	ISS IEA
perinuclear region of cytoplasm	C			IDA
cytoplasm	C			IDA
cytoskeleton	C	IEA	IEA	IEA
soluble fraction	C	TAS		ISS
membrane	C		IEA
ATP binding	F	IEA	IEA IEA	IEA
protein binding	F		IPI	ISS ISS
protein kinase activity	F		IEA
kinase activity	F		IEA
transferase activity	F		IEA	IEA
G-protein-coupled receptor binding	F			IPI
signal transducer activity	F	TAS
transcription factor binding	F			IC
insulin receptor binding	F	TAS		ISS
protein-tyrosine kinase activity	F	IEA	IDA	IMP ISS ISS IEA
Janus kinase activity	F	IEA	IDA	IEA
nucleotide binding	F		IEA	IEA
hormone activity	F	IEA	IEA IEA	IEA
negative regulation of cell proliferation	P			IDA
lymph node development	P		TAS	ISS
gonad development	P			TAS
tyrosine phosphorylation of Stat5 protein	P			IMP
intracellular signaling cascade	P	IEA	IEA	IEA
protein amino acid autophosphorylation	P			IMP
peptidyl-tyrosine phosphorylation	P		IDA	ISS
positive regulation of cAMP biosynthetic process	P			IDA
positive regulation of calcium ion transport	P			IMP
positive regulation of activated T cell proliferation	P			IMP
positive regulation of immune response	P			IMP
protein amino acid phosphorylation	P	IEA	IEA	ISS IEA
negative regulation of apoptosis	P			IDA
cell-cell signaling	P	TAS		ISS
in utero embryonic development	P		IMP	ISS
cytokine and chemokine mediated signaling pathway	P		IDA	IDA
protein kinase cascade	P		IDA
positive regulation of cell proliferation	P			IDA
spermatogenesis	P	TAS		ISS
elevation of cytosolic calcium ion concentration	P			IMP
positive regulation of transcription from RNA polymerase II promoter	P		IMP	ISS
G-protein signaling, adenylate cyclase inhibiting pathway	P			IDA
enzyme linked receptor protein signaling pathway	P		IDA
mesoderm development	P			ISS
male gonad development	P		IMP	IDA ISS
oocyte maturation	P			IDA

Cellular Component

Biological Process

Molecular Function

Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
behavior/neurological phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un Un
immune system phenotype	MP		Un Un Un Un Un Un
nervous system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un Un Un Un
reproductive system phenotype	MP		Un Un
life span-post-weaning/aging	MP		Un

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Cryptorchidism	D			ISS
Severe Combined Immunodeficiency	D			ISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
altered JAK-STAT signaling pathway	W			ISS
JAK-STAT signaling pathway	W			ISSISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway