IpiRecord: IPI00019022

IPI00019022 - ABCB8, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q9NUT2-1
Uniprot ID: ABCB8_HUMAN
Mapping: Chr 7, 150356443 - 150380773
Entrez Gene: 11194
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4244)
Rat: Abcb8, ABC TRANSPORTER 8.
Mouse: Abcb8, ATP-BINDING CASSETTE PROTEIN (FRAGMENT).
Mouse: Abcb8, ATP-BINDING CASSETTE, SUB-FAMILY B (MDR/TAP), MEMBER 8.
Mouse: Abcb8, PROTEIN.
Mouse: Abcb8, 46 KDA PROTEIN.
Mouse: Abcb8, 15 KDA PROTEIN.
Rat: Abcb8, 14 KDA PROTEIN.
Human: ACCN3, ISOFORM 2 OF AMILORIDE-SENSITIVE CATION CHANNEL 3.
Mouse: Accn3, ISOFORM 2 OF AMILORIDE-SENSITIVE CATION CHANNEL 3.
Mouse: Accn3, ISOFORM 1 OF AMILORIDE-SENSITIVE CATION CHANNEL 3.
Mouse: Accn3, ISOFORM 3 OF AMILORIDE-SENSITIVE CATION CHANNEL 3.
Human: ACCN3, ISOFORM 3 OF AMILORIDE-SENSITIVE CATION CHANNEL 3.
Human: ACCN3, ISOFORM 1 OF AMILORIDE-SENSITIVE CATION CHANNEL 3.
Human: ACCN3, ISOFORM 4 OF AMILORIDE-SENSITIVE CATION CHANNEL 3.
Human: ABCB8, MITOCHONDRIAL PRECURSOR.
Human: ABCB8, ATP-BINDING CASSETTE PROTEIN M-ABC1 MRNA.
Human: ABCB8, BINDING CASSETTE, SUB-FAMILY B, MEMBER 8, MITOCHONDRIAL.
Human: ABCB8, BINDING CASSETTE, SUB-FAMILY B, MEMBER 8, MITOCHONDRIAL.
Human: ABCB8, MITOCHONDRIAL PRECURSOR.
Rat: Accn3, AMILORIDE-SENSITIVE CATION CHANNEL 3.
Rat: Accn3, 49 KDA PROTEIN.
Rat: Accn3, ACID SENSING ION CHANNEL 3.

Annotations for ABCB8 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIEA 
integral to plasma membraneCIDA ISS ISS IDA 
integral to membraneCIEA RCA IEA IEA ISS IEA 
membraneCRCA IEA IEA ISS IEA 
ATP-binding cassette (ABC) transporter complexCISS 
mitochondrial envelopeCISS 
membrane fractionCISS 
amiloride-sensitive sodium channel activityFISS IMP IDA 
ATPase activity, coupled to transmembrane movement of substancesFIEA RCA ISS IEA 
ATP bindingFIEA IEA IEA ISS IEA 
transporter activityFISS 
protein bindingFIPI IPI 
sodium ion bindingFIEA IEA 
sodium channel activityFIEA IEA 
ion channel activityFIEA IEA 
cation channel activityFTAS IDA IMP ISS 
ATPase activityFIEA IEA 
nucleotide bindingFIEA IEA IEA 
detection of chemical stimulus during sensory perception of painPIMP IMP ISS 
response to acidPIDA ISS IMP IMP IMP ISS IDA 
detection of temperature stimulus during sensory perceptionPIMP ISS 
cation transportPIDA IMP ISS 
detection of chemical stimulus during sensory perceptionPIMP ISS 
detection of temperature stimulus during sensory perception of painPIMP ISS 
response to mechanical stimulusPIMP IMP ISS 
transportPIEA RCA IEA ISS ISS IEA 
detection of mechanical stimulus during sensory perceptionPIMP ISS 
sodium ion transportPISS IEA IMP IDA 
ion transportPIEA IEA 
detection of mechanical stimulus during sensory perception of painPIMP IMP ISS 
response to heatPIMP IMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn Un
nervous system phenotypeMPUn
touch/vibrissae phenotypeMPUn Un
hearing/vestibular/ear phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ABC transporters - General (02010)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway