IpiRecord: IPI00019471

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
microsome	C	ISS	IDA	ISS IDA ISS
cytoplasm	C	ISS	IDA	ISS ISS
plasma membrane	C			IDA
cytosol	C			IDA
nucleus	C	ISS	IDA	ISS ISS
insulin-like growth factor receptor activity	F			IMP
protein binding	F	IPI IPI IPI	IPI	ISS ISS IPI IDA
signal transducer activity	F	TAS TAS	IEA	ISS IEA
insulin-like growth factor receptor binding	F	IPI		ISS IPI ISS
receptor activity	F		IEA
protein domain specific binding	F			IPI
SH2 domain binding	F	ISS		IPI
phosphoinositide 3-kinase binding	F	IPI ISS		ISS IMP IPI IDA
insulin receptor binding	F	IPI IPI	IEA	ISS IMP ISS
transmembrane receptor protein tyrosine kinase docking protein activity	F	TAS		ISS
protein kinase binding	F	IEA	IDA	ISS IEA
positive regulation of phosphoinositide 3-kinase activity	P			IDA
insulin secretion	P		IMP
protein kinase B signaling cascade	P	IEA	IGI
response to peptide hormone stimulus	P			IDA
insulin-like growth factor receptor signaling pathway	P	IPI		ISS ISS
signal transduction	P	TAS	IEA	ISS IEA
insulin receptor signaling pathway	P	IPI IPI		ISS ISS
protein heterooligomerization	P			IDA

Cellular Component

Biological Process

Molecular Function

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
adipose tissue phenotype	MP		Un Un
endocrine/exocrine gland phenotype	MP		Un Un
homeostasis/metabolism phenotype	MP		Un Un
lethality-embryonic/perinatal	MP		Un
skeleton phenotype	MP		Un Un
cardiovascular system phenotype	MP		Un
limbs/digits/tail phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un
growth/size phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Diabetes Mellitus, Non-Insulin-Dependent	D			ISS
Insulin Resistance	D			ISS
Coronary Arteriosclerosis	D			ISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
insulin-like growth factor signaling pathway	W			IMP
insulin signaling pathway	W			IDAIMP

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type II diabetes mellitus (04930)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway