IPI report for IPI00019581

IpiRecord: IPI00019581

IPI00019581 - F12, COAGULATION FACTOR XII PRECURSOR.
Uniprot Accession: Q96EF3
Uniprot ID: Q96EF3_HUMAN
Mapping: Chr 5, 176761747 - 176769183
Entrez Gene: 2161
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P00748 UniProtKB/Swiss-Prot: FA12_HUMAN REFSEQ_REVIEWED: NP_000496 REFSEQ_REVIEWED: GI:145275213 UniProtKB/TrEMBL: Q8IZZ5 UniProtKB/TrEMBL: Q8IZZ5_HUMAN UniProtKB/TrEMBL: Q96EF3 UniProtKB/TrEMBL: Q96EF3_HUMAN ENSEMBL: ENSP00000374247 ENSEMBL: ENSG00000131187 ENSEMBL: ENSP00000374248 ENSEMBL: ENSG00000131187 H-InvDB: HIT000061501 UniParc: UPI000012A40D HGNC: 3530 Entrez Gene: 2161 UniGene: Hs.1321 CCDS: CCDS34302.1 trome: HTR005718 UTRdb: BB155578 UTRdb: BB200546 UTRdb: BB278948 RZPD: Hs.1321 CleanEx: HS_F12 InterPro: IPR006210 InterPro: IPR000742 InterPro: IPR006209 InterPro: IPR013032 InterPro: IPR014394 InterPro: IPR000083 InterPro: IPR000562 InterPro: IPR000001 InterPro: IPR013806 InterPro: IPR009003 InterPro: IPR001254 InterPro: IPR001314 Pfam: PF00008 Pfam: PF00039 Pfam: PF00040 Pfam: PF00051 Pfam: PF00089 PRINTS: PR00722 PRINTS: PR00013 PRINTS: PR00018 ProDom: PD000995 ProDom: PD000395 SMART: SM00181 SMART: SM00058 SMART: SM00059 SMART: SM00130 SMART: SM00020 PROSITE: PS00022 PROSITE: PS01186 PROSITE: PS50026 PROSITE: PS01253 PROSITE: PS51091 PROSITE: PS00023 PROSITE: PS51092 PROSITE: PS00021 PROSITE: PS50070 PROSITE: PS50240 PROSITE: PS00134 PROSITE: PS00135 SUPERFAMILY: SSF57440 SUPERFAMILY: SSF50494 GENE3D: G3DSA:2.40.20.10 PIRSF: PIRSF001146

IPI00019581 - F12, COAGULATION FACTOR XII PRECURSOR.

Uniprot Accession: Q96EF3

Uniprot ID: Q96EF3_HUMAN

Mapping: Chr 5, 176761747 - 176769183

Entrez Gene: 2161

Entrez MapView: Geneprod

+All IPI Database Cross References

UniProtKB/Swiss-Prot: P00748
UniProtKB/Swiss-Prot: FA12_HUMAN
REFSEQ_REVIEWED: NP_000496
REFSEQ_REVIEWED: GI:145275213
UniProtKB/TrEMBL: Q8IZZ5
UniProtKB/TrEMBL: Q8IZZ5_HUMAN
UniProtKB/TrEMBL: Q96EF3
UniProtKB/TrEMBL: Q96EF3_HUMAN
ENSEMBL: ENSP00000374247
ENSEMBL: ENSG00000131187
ENSEMBL: ENSP00000374248
ENSEMBL: ENSG00000131187
H-InvDB: HIT000061501
UniParc: UPI000012A40D
HGNC: 3530
Entrez Gene: 2161
UniGene: Hs.1321
CCDS: CCDS34302.1
trome: HTR005718
UTRdb: BB155578
UTRdb: BB200546
UTRdb: BB278948
RZPD: Hs.1321
CleanEx: HS_F12
InterPro: IPR006210
InterPro: IPR000742
InterPro: IPR006209
InterPro: IPR013032
InterPro: IPR014394
InterPro: IPR000083
InterPro: IPR000562
InterPro: IPR000001
InterPro: IPR013806
InterPro: IPR009003
InterPro: IPR001254
InterPro: IPR001314
Pfam: PF00008
Pfam: PF00039
Pfam: PF00040
Pfam: PF00051
Pfam: PF00089
PRINTS: PR00722
PRINTS: PR00013
PRINTS: PR00018
ProDom: PD000995
ProDom: PD000395
SMART: SM00181
SMART: SM00058
SMART: SM00059
SMART: SM00130
SMART: SM00020
PROSITE: PS00022
PROSITE: PS01186
PROSITE: PS50026
PROSITE: PS01253
PROSITE: PS51091
PROSITE: PS00023
PROSITE: PS51092
PROSITE: PS00021
PROSITE: PS50070
PROSITE: PS50240
PROSITE: PS00134
PROSITE: PS00135
SUPERFAMILY: SSF57440
SUPERFAMILY: SSF50494
GENE3D: G3DSA:2.40.20.10
PIRSF: PIRSF001146

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13042)
Rat: F12, COAGULATION FACTOR XII.
Mouse: F12, FACTOR XII.
Human: F12, COAGULATION FACTOR XII PRECURSOR.
Human: F12, COAGULATION FACTOR XII.
Human: F12, FACTOR XII (FRAGMENT).
Human: F12, FACTOR XII (FRAGMENT).
Human: F12, FACTOR XII (FRAGMENT).
Human: F12, FACTOR XII (FRAGMENT).

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13042)

Rat: F12, COAGULATION FACTOR XII.

Mouse: F12, FACTOR XII.

Human: F12, COAGULATION FACTOR XII PRECURSOR.

Human: F12, COAGULATION FACTOR XII.

Human: F12, FACTOR XII (FRAGMENT).

Annotations for F12 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C		RCA	ISS IDA
extracellular region	C	NAS	RCA	ISS IEA
trypsin activity	F		RCA	ISS
hydrolase activity	F		IEA
serine-type endopeptidase activity	F	IEA	IEA	IEA
coagulation factor XIa activity	F	TAS
peptidase activity	F		IEA
catalytic activity	F	IEA
coagulation factor XIIa activity	F	TAS		ISS IDA
chymotrypsin activity	F		RCA	ISS
proteolysis	P	IEA	RCA	ISS IEA
fibrinolysis	P	IEA
blood coagulation	P	TAS		ISS IDA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Factor XII Deficiency	D			ISS
Angioneurotic Edema	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway