IPI report for IPI00019591

IpiRecord: IPI00019591

IPI00019591 - CFB, ISOFORM 1 OF COMPLEMENT FACTOR B PRECURSOR (FRAGMENT).
Uniprot Accession: Q53F89
Uniprot ID: Q53F89_HUMAN
Mapping: Chr 6, 32048579 - 32054666
Entrez Gene: 629
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P00751-1 UniProtKB/Swiss-Prot: CFAB_HUMAN Vega: OTTHUMP00000029283 Vega: OTTHUMP00000174690 Vega: OTTHUMP00000029723 Vega: OTTHUMP00000174736 REFSEQ_REVIEWED: NP_001701 REFSEQ_REVIEWED: GI:67782358 UniProtKB/TrEMBL: Q53F89 UniProtKB/TrEMBL: Q53F89_HUMAN ENSEMBL: ENSP00000299370 ENSEMBL: ENSG00000166285 ENSEMBL: ENSP00000364604 ENSEMBL: ENSG00000204359 H-InvDB: HIT000191367 UniParc: UPI000000D7F8 HGNC: 1037 Entrez Gene: 629 UniGene: Hs.69771 CCDS: CCDS4729.1 Transfac: G000231 UTRdb: BB085026 UTRdb: BB201391 UTRdb: BB332581 UTRdb: BB334083 UTRdb: BB379924 UTRdb: BB380332 UTRdb: BB381792 RZPD: Hs.69771 InterPro: IPR011360 InterPro: IPR009003 InterPro: IPR001254 InterPro: IPR001314 InterPro: IPR000436 InterPro: IPR002035 Pfam: PF00084 Pfam: PF00089 Pfam: PF00092 PRINTS: PR00722 PRINTS: PR00453 SMART: SM00032 SMART: SM00020 SMART: SM00327 PROSITE: PS50923 PROSITE: PS50240 PROSITE: PS00134 PROSITE: PS00135 PROSITE: PS50234 SUPERFAMILY: SSF50494 PIRSF: PIRSF001154

IPI00019591 - CFB, ISOFORM 1 OF COMPLEMENT FACTOR B PRECURSOR (FRAGMENT).

Uniprot Accession: Q53F89

Uniprot ID: Q53F89_HUMAN

Mapping: Chr 6, 32048579 - 32054666

Entrez Gene: 629

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14230)
Rat: Cfb, DA1-24.
Mouse: Cfb, COMPLEMENT FACTOR B PRECURSOR (FRAGMENT).
Rat: Cfb, B-FACTOR, PROPERDIN.
Rat: Cfb, 83 KDA PROTEIN.
Human: CFB, ISOFORM 1 OF COMPLEMENT FACTOR B PRECURSOR (FRAGMENT).
Human: CFB, ISOFORM 2 OF COMPLEMENT FACTOR B PRECURSOR (FRAGMENT).
Human: CFB, B-FACTOR, PROPERDIN.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14230)

Rat: Cfb, DA1-24.

Mouse: Cfb, COMPLEMENT FACTOR B PRECURSOR (FRAGMENT).

Rat: Cfb, B-FACTOR, PROPERDIN.

Rat: Cfb, 83 KDA PROTEIN.

Human: CFB, ISOFORM 1 OF COMPLEMENT FACTOR B PRECURSOR (FRAGMENT).

Human: CFB, ISOFORM 2 OF COMPLEMENT FACTOR B PRECURSOR (FRAGMENT).

Human: CFB, B-FACTOR, PROPERDIN.

Annotations for CFB and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular region	C	IEA	IEA	IEA
hydrolase activity	F		IEA
trypsin activity	F		RCA	ISS
peptidase activity	F	IEA	IEA	IEA
alternative-complement-pathway C3/C5 convertase activity	F		IEA
serine-type endopeptidase activity	F	IEA	IEA IEA	IEA
chymotrypsin activity	F		RCA	ISS
complement activation	P	IEA	IEA	IEA
innate immune response	P		IEA
cell proliferation	P		TAS	ISS
complement activation, alternative pathway	P		TAS IMP	ISS
immune response	P		IEA
proteolysis	P	IEA	RCA	IEA ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Mouse
immune system phenotype	MP	Un Un Un
normal phenotype	MP	Un
reproductive system phenotype	MP	Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway