| IPI00020332 - ARG2, ARGINASE-2, MITOCHONDRIAL PRECURSOR. | |
|---|---|
| Uniprot Accession: P78540 | |
| Uniprot ID: ARGI2_HUMAN | |
| Mapping: Chr 14, 67156332 - 67188190 | |
| Entrez Gene: 384 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6356) |
|---|
| Rat: Arg2, ARGINASE-2, MITOCHONDRIAL PRECURSOR. |
| Mouse: Arg2, ARGINASE-2, MITOCHONDRIAL PRECURSOR. |
| Human: ARG2, ARGINASE-2, MITOCHONDRIAL PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| mitochondrion | C | TAS | ISS | IMP ISS IDA IDA |
| hydrolase activity | F | IEA | IEA | IEA |
| arginase activity | F | TAS | ISS | IDA ISS IDA IDA |
| metal ion binding | F | IEA | IEA IEA | IEA |
| protein binding | F | ISS | IPI IPI | |
| nitric-oxide synthase binding | F | IPI | ||
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | F | IEA | ||
| manganese ion binding | F | IEA | IEA | IEA |
| nitric oxide biosynthetic process | P | TAS | ISS | |
| urea cycle | P | IEA | IEA | IEA |
| arginine catabolic process to ornithine | P | TAS | ||
| striated muscle contraction | P | IEA | IMP | ISS IEA |
| arginine metabolic process | P | IEA | IMP | |
| arginine catabolic process | P | IEA | IEA | |
| regulation of nitric oxide biosynthetic process | P | IEP | ||
| negative regulation of nitric-oxide synthase activity | P | IMP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Sepsis | D | IEP | ||
| Liver Cirrhosis, Experimental | D | IEP | ||
| Hypertension | D | IEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| arginine and proline metabolic pathway | W | IEA | ||
| pathway of urea cycle and metabolism of amino groups | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Arginine and proline metabolism (00330) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Urea cycle and metabolism of amino groups (00220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |