| IPI00020985 - EP300, HISTONE ACETYLTRANSFERASE P300. | |
|---|---|
| Uniprot Accession: Q7Z6C1 | |
| Uniprot ID: Q7Z6C1_HUMAN | |
| Mapping: Chr 22, 39817736 - 39905472 | |
| Entrez Gene: 2033 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7254) |
|---|
| Rat: Ep300, SIMILAR TO E1A BINDING PROTEIN P300. |
| Mouse: Ep300, E1A BINDING PROTEIN P300. |
| Mouse: Ep300, SEQUENCE. |
| Rat: Ep300, E1A-BINDING PROTEIN. |
| Human: EP300, HISTONE ACETYLTRANSFERASE P300. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleus | C | IDA | IDA IDA | IEA ISS |
| transcription factor complex | C | IDA | ISS IC | |
| histone acetyltransferase complex | C | IEA | IDA | ISS |
| histone acetyltransferase activity | F | IDA | IDA | ISS |
| acetyltransferase activity | F | IMP | ||
| transcription activator activity | F | IDA IDA | ISS IMP | |
| transcription factor activity | F | TAS | IMP | |
| peroxisome proliferator activated receptor binding | F | IDA | ||
| metal ion binding | F | IEA | ||
| protein binding | F | IPI IPI IPI | ISS | |
| transferase activity | F | IEA | ||
| protein C-terminus binding | F | TAS | ||
| transcription cofactor activity | F | IEA | ||
| transcription coactivator activity | F | IDA IEP IDA | IDA | ISS |
| DNA binding | F | IDA IDA | ISS | |
| transcription factor binding | F | IPI | ||
| zinc ion binding | F | IEA | IEA | |
| homeostatic process | P | TAS | ||
| positive regulation of transcription factor activity | P | IDA | ||
| N-terminal peptidyl-lysine acetylation | P | IDA | ||
| response to hypoxia | P | IDA | ||
| striated muscle development | P | IEA | IMP | ISS |
| regulation of transcription | P | IDA | ISS | |
| apoptosis | P | IMP | ||
| nervous system development | P | TAS | ||
| lung development | P | IEA | IMP | ISS |
| heart development | P | IEA | IMP | ISS |
| cell cycle | P | IEA | ||
| regulation of transcription, DNA-dependent | P | IDA | IEA ISS | |
| organ morphogenesis | P | IEA | IMP | ISS |
| positive regulation of transcription, DNA-dependent | P | IDA | ISS | |
| positive regulation of transcription from RNA polymerase II promoter | P | IEA | IGI | IMP |
| histone acetylation | P | IEA | ||
| signal transduction | P | NAS | ||
| somitogenesis | P | IEA | IGI | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un | ||
| craniofacial phenotype | MP | Un Un | ||
| growth/size phenotype | MP | Un Un Un | ||
| immune system phenotype | MP | Un Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un | ||
| lethality-postnatal | MP | Un Un | ||
| muscle phenotype | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un Un Un | ||
| respiratory system phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un | ||
| tumorigenesis | MP | Un Un Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un | ||
| nervous system phenotype | MP | Un | ||
| cardiac hypertrophy | N | IED |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Rubinstein-Taybi Syndrome | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| TGF-beta signaling pathway (04350) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Cell cycle (04110) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Adherens junction (04520) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Jak-STAT signaling pathway (04630) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Huntington's disease (05040) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Long-term potentiation (04720) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Notch signaling pathway (04330) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Neurodegenerative Disorders (01510) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |