IpiRecord: IPI00021798

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
interleukin-12 complex	C			IDA
membrane	C	IEA	IEA	IEA
extracellular space	C	TAS	IDA IDA IDA	ISS IDA
protein heterodimerization activity	F			IDA
protein kinase activity	F			ISS
protein binding	F	IPI
receptor activity	F			IEA
signal transducer activity	F	TAS
interleukin-12 alpha subunit binding	F		IPI	ISS IDA
ATP binding	F			ISS
hematopoietin/interferon-class (D200-domain) cytokine receptor activity	F	IEA	IEA	IEA
protein serine/threonine kinase activity	F			ISS
protein homodimerization activity	F		IDA	ISS
cytokine activity	F	IEA	IDA	ISS
interleukin-12 receptor binding	F	TAS
interferon-gamma biosynthetic process	P	TAS
positive regulation of activated T cell proliferation	P	IDA
T-helper 1 type immune response	P	TAS
protein amino acid phosphorylation	P			ISS
natural killer cell activation during immune response	P			IMP
cell surface receptor linked signal transduction	P		IDA	ISS
positive regulation of interferon-gamma biosynthetic process	P	TAS
regulation of cytokine biosynthetic process	P	TAS
positive regulation of T cell proliferation	P		IDA
natural killer cell activation	P	IDA
sensory perception of pain	P			IDA
T-helper cell differentiation	P	IDA

Cellular Component

Biological Process

Molecular Function

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
immune system phenotype	MP		Un Un
tumorigenesis	MP		Un
digestive/alimentary phenotype	MP		Un
hematopoietic system phenotype	MP		Un

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Salmonella Infections	D			ISS
Asthma	D			ISS
Mycobacterium Infections, Atypical	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Toll-like receptor signaling pathway (04620)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type I diabetes mellitus (04940)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway