IpiRecord: IPI00021842

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
chylomicron	C	IEA	IEA	IEA
Golgi apparatus	C			IDA
cytoplasm	C	TAS		ISS IDA
extracellular region	C	NAS TAS	IEA	ISS IEA
extracellular space	C		RCA IDA IDA IDA IDA	ISS IDA
extrinsic to external side of plasma membrane	C			IDA
cholesterol transporter activity	F		IDA
lipid binding	F		IEA	IEA
apolipoprotein E receptor binding	F	NAS		ISS
heparin binding	F	NAS	IEA	ISS IEA
antioxidant activity	F	NAS		ISS ISS
beta-amyloid binding	F	IDA		ISS ISS
lipid transporter activity	F	IEA	IEA	IDA IEA
phospholipid binding	F	TAS		ISS
lipoprotein binding	F	IEA	IDA	ISS IEA
tau protein binding	F	TAS		ISS
cholesterol metabolic process	P		IMP IMP	ISS
cellular calcium ion homeostasis	P	IEA	IDA	ISS IEA
cholesterol catabolic process	P	IEA	IMP	ISS IEA
synaptogenesis	P			ISS
lipoprotein metabolic process	P	NAS	IEA	ISS IEA
response to reactive oxygen species	P	NAS		ISS
neurite regeneration	P			TAS
axon regeneration	P		IGI
protein localization	P		IMP
cytoskeleton organization and biogenesis	P	TAS		ISS
lipid transport	P	TAS	IEA IEA	IDA ISS IEA
synaptic transmission, cholinergic	P	TAS		ISS
response to oxidative stress	P		IMP	ISS IEA
circulation	P	NAS		ISS
regulation of neuronal synaptic plasticity	P	TAS		ISS
learning and/or memory	P	TAS		ISS
induction of apoptosis	P	IDA		ISS ISS
lipoprotein biosynthetic process	P		IGI
transport	P		IEA
protein tetramerization	P	IDA		ISS IEA
cholesterol homeostasis	P	TAS	IMP IMP	ISS ISS
response to ethanol	P			IDA
cholesterol efflux	P		IMP IDA
regulation of axon extension	P	TAS		ISS
intracellular transport	P	TAS		ISS
vasodilation	P	IEA	IMP	ISS IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (19)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
adipose tissue phenotype	MP		Un
cellular phenotype	MP		Un Un
skin/coat/nails phenotype	MP		Un Un
endocrine/exocrine gland phenotype	MP		Un
behavior/neurological phenotype	MP		Un Un Un
homeostasis/metabolism phenotype	MP		Un Un Un Un Un Un Un Un Un
immune system phenotype	MP		Un Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un
nervous system phenotype	MP		Un Un Un Un Un
vision/eye phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un Un Un Un Un
hearing/vestibular/ear phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un
no phenotypic analysis	MP		Un
growth/size phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un
life span-post-weaning/aging	MP		Un Un Un

Disease (15)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Cerebrovascular Disorders	D			ISS
Hypertriglyceridemia	D			ISSISS
Obesity	D			ISS
Hypercholesterolemia	D			ISS
Memory Disorders	D			ISS
Myocardial Infarction	D			ISS
Diabetes Mellitus, Experimental	D			IEP
Cardiomyopathy, Congestive	D			ISS
Myocardial Ischemia	D			ISS
Hyperlipoproteinemia Type III	D			ISS
Coronary Arteriosclerosis	D			ISSISS
Aortic Aneurysm, Abdominal	D			ISS
Hyperlipidemia, Familial Combined	D			ISSISS
Coronary Disease	D			ISS
Cerebral Infarction	D			ISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
altered lipoprotein metabolic pathway	W			ISS
Alzheimer disease pathway	W			IEA
lipoprotein metabolic pathway	W			ISS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Alzheimer's disease (05010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Neurodegenerative Disorders (01510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway