IpiRecord: IPI00021983

IPI00021983 - NCSTN, ISOFORM 1 OF NICASTRIN PRECURSOR.
Uniprot Accession: Q5T208
Uniprot ID: Q5T208_HUMAN
Mapping: Chr 1, 158579678 - 158595366
Entrez Gene: 23385
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_17746)
Rat: Ncstn, ISOFORM 1 OF NICASTRIN PRECURSOR.
Human: NCSTN, ISOFORM 1 OF NICASTRIN PRECURSOR.
Human: NCSTN, ISOFORM 2 OF NICASTRIN PRECURSOR.
Human: NCSTN, NICASTRIN.
Human: NCSTN, NICASTRIN.
Human: NCSTN, NICASTRIN.
Human: NCSTN, NICASTRIN.
Human: NCSTN, NICASTRIN.
Human: NCSTN, NICASTRIN.
Rat: Ncstn, ISOFORM 2 OF NICASTRIN PRECURSOR.

Annotations for NCSTN and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCISS 
membrane fractionCISS 
integral to membraneCIEA ISS 
lysosomal membraneCIDA 
endoplasmic reticulumCISS 
Golgi apparatusCISS 
protein bindingFISS 
peptidase activityFIPI 
Notch receptor processingPISS 
positive regulation of enzyme activityPISS 
protein processingPIEA IEP ISS 
amyloid precursor protein catabolic processPISS 
membrane protein ectodomain proteolysisPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
Notch signaling pathwayWTAS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway
Notch signaling pathway (04330)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway