| IPI00022872 - LIMK2, ISOFORM LIMK2A OF LIM DOMAIN KINASE 2. | |
|---|---|
| Uniprot Accession: P53671-1 | |
| Uniprot ID: LIMK2_HUMAN | |
| Mapping: Chr 22, 29938250 - 30006066 | |
| Entrez Gene: 3985 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11973) |
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| Rat: Limk2, ISOFORM LIMK2A OF LIM DOMAIN KINASE 2. |
| Mouse: Limk2, ISOFORM 1 OF LIM DOMAIN KINASE 2. |
| Mouse: Limk2, ISOFORM 3 OF LIM DOMAIN KINASE 2. |
| Mouse: Limk2, ISOFORM 2 OF LIM DOMAIN KINASE 2. |
| Mouse: Limk2, LIM MOTIF-CONTAINING PROTEIN KINASE 2. |
| Rat: Limk2, ISOFORM LIMK2B OF LIM DOMAIN KINASE 2. |
| Rat: Limk2, ISOFORM LIMK2C OF LIM DOMAIN KINASE 2. |
| Rat: Limk2, ISOFORM LIMK2D OF LIM DOMAIN KINASE 2. |
| Rat: Limk2, 71 KDA PROTEIN. |
| Rat: Limk2, 51 KDA PROTEIN. |
| Human: LIMK2, ISOFORM LIMK2A OF LIM DOMAIN KINASE 2. |
| Human: LIMK2, LIM DOMAIN KINASE 2 ISOFORM 1. |
| Human: LIMK2, ISOFORM LIMK2B OF LIM DOMAIN KINASE 2. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleus | C | IDA | IDA ISS ISS | |
| cytoplasm | C | IDA | ISS ISS | |
| cis-Golgi network | C | IDA | ISS | |
| soluble fraction | C | IDA | ||
| protein heterodimerization activity | F | IPI | ISS | |
| metal ion binding | F | IEA | IEA | |
| ATP binding | F | IEA | IEA IEA | |
| protein-tyrosine kinase activity | F | IEA | ||
| kinase activity | F | IEA | ||
| protein serine/threonine kinase activity | F | IEA IEA | TAS IDA ISS | |
| protein binding | F | IEA | IEA | |
| protein kinase activity | F | IEA | IMP | ISS |
| transferase activity | F | IEA | ||
| nucleotide binding | F | IEA | IEA | |
| zinc ion binding | F | IEA | IEA IEA | |
| spermatogenesis | P | IMP | ISS | |
| protein amino acid phosphorylation | P | IEA | IMP | IDA ISS |
| stress fiber formation | P | ISS | ||
| spermatid development | P | TAS | ||
| focal adhesion formation | P | ISS | ||
| regulation of cytoskeleton organization and biogenesis | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Rho/Rac/Cdc42 mediated signaling pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |