IpiRecord: IPI00023599

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C		IDA	IDA
integral to plasma membrane	C			ISS
integral to membrane	C		RCA	ISS
membrane	C		IEA IEA
cytoplasm	C			IDA
nucleus	C		IDA	IDA
mitochondrion	C			IDA
cell soma	C			IDA
extrinsic to membrane	C		IDA	ISS
peptide hormone binding	F		IPI	IDA
growth hormone receptor activity	F		IDA	TAS ISS IDA
hematopoietin/interferon-class (D200-domain) cytokine receptor activity	F		IEA
protein kinase binding	F			IPI
receptor activity	F		IEA	IEA
protein binding	F		IPI	ISS
protein phosphatase binding	F			IPI IMP
SH2 domain binding	F			IPI IMP IDA
positive regulation of JAK-STAT cascade	P			IDA IMP
endocytosis	P		IEA
neuroprotection	P			IDA
positive regulation of cell differentiation	P			IEP TAS
skeletal development	P			ISS
growth	P			ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
adipose tissue phenotype	MP		Un Un
growth/size phenotype	MP		Un Un Un
homeostasis/metabolism phenotype	MP		Un
liver/biliary system phenotype	MP		Un Un
reproductive system phenotype	MP		Un
immune system phenotype	MP		Un
hematopoietic system phenotype	MP		Un
nervous system phenotype	MP		Un Un
renal/urinary system phenotype	MP		Un Un
abnormal skeleton physiology	N			IEA
increased circulating growth hormone level	N			IEA
abnormal skeleton morphology	N			IEA
decreased body height	N			IEA

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Dwarfism, Pituitary	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
growth hormone signaling pathway	W			IDA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway