IpiRecord: IPI00023868

IPI00023868 - ABCC2, CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 1.
Uniprot Accession: Q5T2B1
Uniprot ID: Q5T2B1_HUMAN
Mapping: Chr 10, 101532479 - 101601939
Entrez Gene: 1244
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1752)
Rat: Abcc2, CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 1.
Mouse: Abcc2, ATP-BINDING CASSETTE, SUB-FAMILY C, MEMBER 2.
Mouse: Abcc2, CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 1.
Mouse: Abcc2, ATP-BINDING CASSETTE PROTEIN (FRAGMENT).
Rat: Abcc2, SIMILAR TO CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 1.
Human: ABCC2, CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 1.
Human: ABCC2, ATP-BINDING CASSETTE, SUB-FAMILY C (CFTR/MRP), MEMBER 2.
Human: ABCC2, CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER (FRAGMENT).

Annotations for ABCC2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS IDA ISS ISS 
membrane fractionCIDA 
integral to membraneCIEA IEA IEA 
membraneCIEA RCA IDA ISS IEA 
apical plasma membraneCIDA ISS 
intercellular canaliculusCIDA ISS 
transporter activityFIEA IEA IEA 
ATP bindingFIEA IEA IEA IEA IEA 
protein bindingFIPI ISS 
nucleotide bindingFIEA RCA ISS IEA 
organic anion transmembrane transporter activityFTAS TAS ISS 
ATPase activity, coupled to transmembrane movement of substancesFTAS IEA ISS IEA 
nucleoside-triphosphatase activityFIEA 
ATPase activityFIEA IEA IEA 
response to oxidative stressPIEP 
multidrug transportPIMP 
response to methotrexatePIEP 
prostaglandin transportPIMP 
cellular chloride ion homeostasisPIDA 
organic anion transportPTAS 
response to steroid hormone stimulusPIEP 
response to arsenicPIEP 
transportPTAS IEA IEA ISS IEA 
response to heatPIEP 
response to drugPIDA 
response to estrogen stimulusPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
liver/biliary system phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
renal/urinary system phenotypeMPUn
jaundiceNIED
abnormal blood-brain barrier functionNIED

Disease (7)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
CholestasisDIEP
Kidney Failure, ChronicDIED
HyperbilirubinemiaDIED
Fatty LiverDIEP
Status EpilepticusDIEP
EndotoxemiaDIEP
Jaundice, Chronic IdiopathicDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
multidrug resistance-associated protein mediated transport pathwayWTAS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ABC transporters - General (02010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway