IpiRecord: IPI00023875

IPI00023875 - CASP9, ISOFORM 1 OF CASPASE-9 PRECURSOR.
Uniprot Accession: Q53Y70
Uniprot ID: Q53Y70_HUMAN
Mapping: Chr 1, 15687322 - 15723527
Entrez Gene: 842
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5642)
Rat: Casp9_v1, CASPASE-9.
Mouse: Casp9, CASP9 PROTEIN.
Mouse: Casp9, CASPASE 9.
Mouse: Casp9, CASPASE 9.
Rat: Casp9_v1, CASPASE-9 CTD ISOFORM.
Rat: Casp9_v1, CASPASE-9 DOMINANT NEGATIVE FORM.
Human: CASP9, ISOFORM 1 OF CASPASE-9 PRECURSOR.
Human: CASP9, ISOFORM 2 OF CASPASE-9 PRECURSOR.
Human: CASP9, CASPASE 9, APOPTOSIS-RELATED CYSTEINE PEPTIDASE.
Human: CASP9, CASPASE 9, APOPTOSIS-RELATED CYSTEINE PEPTIDASE.
Human: CASP9, CASPASE 9, APOPTOSIS-RELATED CYSTEINE PEPTIDASE.
Human: CASP9, CASPASE 9 ISOFORM ALPHA PREPROPROTEIN VARIANT (FRAGMENT).

Annotations for CASP9 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCIDA ISS 
soluble fractionCIDA ISS 
intracellularCIEA RCA IEA ISS 
nucleusCIDA ISS 
cysteine-type peptidase activityFIEA IEA IEA 
hydrolase activityFIEA 
caspase activityFIEA RCA IDA IDA IEA ISS ISS 
peptidase activityFIEA 
protein bindingFIEA IPI IEA ISS ISS 
enzyme activator activityFISS 
apoptosisPIEA RCA ISS 
induction of apoptosisPRCA ISS 
caspase activation via cytochrome cPISS 
regulation of apoptosisPIEA RCA IEA ISS 
proteolysisPIEA RCA RCA IEA ISS 
apoptotic programPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un
immune system phenotypeMPUn Un
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn Un
lethality-postnatalMPUn
taste/olfaction phenotypeMPUn
nervous system phenotypeMPUn Un
cardiovascular system phenotypeMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway