| IPI00024107 - SNCA, ISOFORM 1 OF ALPHA-SYNUCLEIN. | |
|---|---|
| Uniprot Accession: P37840-1 | |
| Uniprot ID: SYUA_HUMAN | |
| Mapping: Chr 4, 90866479 - 90978470 | |
| Entrez Gene: 6622 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4631) |
|---|
| Rat: Snca, ISOFORM SYN1 OF ALPHA-SYNUCLEIN. |
| Mouse: Snca, ISOFORM 1 OF ALPHA-SYNUCLEIN. |
| Mouse: Snca, ISOFORM 2 OF ALPHA-SYNUCLEIN. |
| Rat: Snca, ISOFORM SYN2 OF ALPHA-SYNUCLEIN. |
| Rat: Snca, ISOFORM SYN3 OF ALPHA-SYNUCLEIN. |
| Human: SNCA, ISOFORM 1 OF ALPHA-SYNUCLEIN. |
| Human: SNCA, ISOFORM 2-4 OF ALPHA-SYNUCLEIN. |
| Human: SNCA, ISOFORM 2-5 OF ALPHA-SYNUCLEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| synaptosome | C | IDA | ISS | |
| cytoplasm | C | IEA IEA | IDA ISS | |
| protein N-terminus binding | F | IPI | ||
| protein binding | F | ISS | ||
| identical protein binding | F | IDA | ISS | |
| synaptic transmission, dopaminergic | P | IMP IMP | ISS | |
| regulation of long-term neuronal synaptic plasticity | P | IMP | ISS | |
| phospholipid metabolic process | P | IMP | ISS | |
| regulation of locomotion | P | IMP | ISS | |
| regulation of neurotransmitter secretion | P | IMP IMP IMP | ISS | |
| dopamine metabolic process | P | IGI | ISS | |
| dopamine biosynthetic process | P | IMP | ISS | |
| central nervous system development | P | ISS | ||
| anti-apoptosis | P | ISS | ||
| positive regulation of neurotransmitter secretion | P | IDA | ISS | |
| response to drug | P | IMP | ISS | |
| synaptic vesicle transport | P | IMP | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nervous system phenotype | MP | Un Un | ||
| decreased dopamine level | N | ISS | ||
| abnormal locomotor activity | N | ISS | ||
| alcohol preference | N | ISS | ||
| hypoactivity | N | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Parkinson disease pathway | W | IEA IDA | ||
| altered ubiquitin/proteasome degradation pathway | W | ISS | ||
| ubiquitin/proteasome degradation pathway | W | ISS | ||
| Alzheimer disease pathway | W | IEA ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Alzheimer's disease (05010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Parkinson's disease (05020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Neurodegenerative Disorders (01510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |