IpiRecord: IPI00025100

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
integral to membrane	C	IEA	IEA
extracellular space	C		RCA	ISS
membrane	C	IEA	IEA
mitochondrion	C	TAS	IDA	TAS ISS ISS IEA
cellular_component	C			ND
mitochondrial alpha-ketoglutarate dehydrogenase complex	C	IDA		ISS ISS
potassium ion binding	F	IEA	IEA	IEA
protein complex binding	F			IPI
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	F	IEA	IEA	IEA
carboxy-lyase activity	F	TAS		ISS
oxidoreductase activity	F		IEA
metal ion binding	F	IEA	IEA	IEA
protein binding	F	IPI IPI
cyclin-dependent protein kinase 5 activator regulator activity	F		IDA	ISS IEA
2-oxoisovalerate dehydrogenase (acylating) activity	F			TAS
molecular_function	F			ND
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	F	TAS IEA	IEA	ISS IEA
alpha-ketoacid dehydrogenase activity	F	IDA		TAS ISS ISS
metabolic process	P	IEA	IEA	IEA
response to cAMP	P			IEP
response to nutrient	P			IEP
branched chain family amino acid catabolic process	P	IDA		TAS ISS ISS
response to glucocorticoid stimulus	P			IEP
positive regulation of transcription, DNA-dependent	P		IDA	ISS IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un
adipose tissue phenotype	MP		Un
behavior/neurological phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
lethality-postnatal	MP		Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un
nervous system phenotype	MP		Un
reproductive system phenotype	MP		Un
growth/size phenotype	MP		Un
life span-post-weaning/aging	MP		Un
liver/biliary system phenotype	MP		Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Diabetes Mellitus, Experimental	D			IEP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Valine, leucine and isoleucine degradation (00280)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway