| IPI00025307 - CYP27A1, CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR. | |
|---|---|
| Uniprot Accession: Q02318 | |
| Uniprot ID: CP27A_HUMAN | |
| Mapping: Chr 2, 219354745 - 219388254 | |
| Entrez Gene: 1593 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8844) |
|---|
| Rat: Cyp27a1, CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR. |
| Mouse: Cyp27a1, CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR. |
| Human: CYP27A1, CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| mitochondrial inner membrane | C | IEA | IDA | IEA ISS |
| mitochondrion | C | IEA | IDA | IEA ISS IDA |
| mitochondrial envelope | C | IDA | ||
| membrane | C | IEA | IEA | IEA |
| steroid hydroxylase activity | F | TAS | ||
| oxidoreductase activity | F | IEA | ||
| iron ion binding | F | IEA | IEA IEA | IEA |
| cholesterol 26-hydroxylase activity | F | IDA | ||
| metal ion binding | F | IEA | IEA | IEA |
| vitamin D3 25-hydroxylase activity | F | IDA | ||
| heme binding | F | IEA | IEA | IEA |
| monooxygenase activity | F | IEA IEA | IEA | |
| cholestanetriol 26-monooxygenase activity | F | IEA | IEA | IEA |
| steroid catabolic process | P | TAS | ||
| cholesterol metabolic process | P | IDA | ||
| electron transport | P | IEA | RCA | IEA ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Xanthomatosis, Cerebrotendinous | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| reverse cholesterol transport pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| PPAR signaling pathway (03320) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Bile acid biosynthesis (00120) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |