IpiRecord: IPI00025307

IPI00025307 - CYP27A1, CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q02318
Uniprot ID: CP27A_HUMAN
Mapping: Chr 2, 219354745 - 219388254
Entrez Gene: 1593
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8844)
Rat: Cyp27a1, CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR.
Mouse: Cyp27a1, CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR.
Human: CYP27A1, CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR.

Annotations for CYP27A1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
mitochondrial inner membraneCIEA IDA IEA ISS 
mitochondrionCIEA IDA IEA ISS IDA 
mitochondrial envelopeCIDA 
membraneCIEA IEA IEA 
steroid hydroxylase activityFTAS 
oxidoreductase activityFIEA 
iron ion bindingFIEA IEA IEA IEA 
cholesterol 26-hydroxylase activityFIDA 
metal ion bindingFIEA IEA IEA 
vitamin D3 25-hydroxylase activityFIDA 
heme bindingFIEA IEA IEA 
monooxygenase activityFIEA IEA IEA 
cholestanetriol 26-monooxygenase activityFIEA IEA IEA 
steroid catabolic processPTAS 
cholesterol metabolic processPIDA 
electron transportPIEA RCA IEA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
liver/biliary system phenotypeMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Xanthomatosis, CerebrotendinousDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
reverse cholesterol transport pathwayWISS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
PPAR signaling pathway (03320)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Bile acid biosynthesis (00120)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway