| IPI00025380 - ITGAL, ISOFORM 1 OF INTEGRIN ALPHA-L PRECURSOR. | |
|---|---|
| Uniprot Accession: P20701-1 | |
| Uniprot ID: ITAL_HUMAN | |
| Mapping: Chr 16, 30391551 - 30441772 | |
| Entrez Gene: 3683 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1240) |
|---|
| Rat: Itgal, INTEGRIN ALPHA L. |
| Mouse: Itgal, INTEGRIN ALPHA-L PRECURSOR. |
| Mouse: Itgal, CLONE:C630032K18 PRODUCT:INTEGRIN ALPHA L, FULL INSERT SEQUENCE. |
| Mouse: Itgal, CLONE:F830013L17 PRODUCT:INTEGRIN ALPHA L, FULL INSERT SEQUENCE. |
| Human: ITGAL, ISOFORM 1 OF INTEGRIN ALPHA-L PRECURSOR. |
| Human: ITGAL, ISOFORM 2 OF INTEGRIN ALPHA-L PRECURSOR. |
| Human: ITGAL, ITGAL PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integrin complex | C | IEA | IEA | ISS IEA |
| integral to membrane | C | IEA | RCA | ISS IEA |
| membrane | C | IEA | ||
| cell surface | C | IDA | ||
| immunological synapse | C | IDA | ||
| plasma membrane | C | IEA | ||
| calcium ion binding | F | IEA | ||
| magnesium ion binding | F | IEA | ||
| protein heterodimerization activity | F | IPI | ||
| receptor activity | F | IEA | IEA | IEA |
| protein binding | F | IEA | IEA | IEA |
| cell-cell adhesion | P | IMP | ||
| leukocyte adhesion | P | IDA | ||
| signal transduction | P | ISS | ||
| integrin-mediated signaling pathway | P | IEA | IEA | IEA |
| cell adhesion | P | IEA | IEA IEA | ISS IEA |
| activated T cell proliferation | P | IMP | ISS | |
| inflammatory response | P | ISS | ||
| cell motility | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| immune system phenotype | MP | Un Un Un | ||
| hematopoietic system phenotype | MP | Un Un Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integrin signaling pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Cell adhesion molecules (CAMs) (04514) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |