IpiRecord: IPI00025394

IPI00025394 - DDC, AROMATIC-L-AMINO-ACID DECARBOXYLASE.
Uniprot Accession: Q75MJ6
Uniprot ID: Q75MJ6_HUMAN
Mapping: Chr 7, 50493657 - 50600537
Entrez Gene: 1644
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11925)
Rat: Ddc, AROMATIC L-AMINO ACID DECARBOXYLASE.
Mouse: Ddc, AROMATIC-L-AMINO-ACID DECARBOXYLASE.
Mouse: Ddc, DOPA DECARBOXYLASE.
Mouse: Ddc, CLONE:3110085H16 PRODUCT:DOPA DECARBOXYLASE, FULL INSERT SEQUENCE.
Rat: Ddc, AROMATIC-L-AMINO-ACID DECARBOXYLASE.
Rat: Ddc, 15 KDA PROTEIN.
Human: DDC, AROMATIC-L-AMINO-ACID DECARBOXYLASE.
Human: DDC, UNCHARACTERIZED PROTEIN DDC.
Human: DDC, PUTATIVE L-DOPA DECARBOXYLASE (FRAGMENT).

Annotations for DDC and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
intracellularCTAS 
carboxy-lyase activityFIEA IEA IEA 
aromatic-L-amino-acid decarboxylase activityFTAS IEA ISS ISS IEA IDA 
lyase activityFIEA IEA IEA 
catalytic activityFIEA 
pyridoxal phosphate bindingFIEA IEA TAS IEA 
catecholamine biosynthetic processPIEA IEA IEA TAS 
dopamine metabolic processPTAS 
serotonin metabolic processPTAS 
circadian rhythmPIEP 
amino acid and derivative metabolic processPIEA IEA IEA 
carboxylic acid metabolic processPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (1)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
lethality-postnatalMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Metabolism, Inborn ErrorsDISS

Pathway (5)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
phenylalanine metabolic pathwayWIEA
tyrosine metabolic pathwayWIEA
histidine metabolic pathwayWIEA
alkaloid biosynthetic pathway IWIEA
tryptophan metabolic pathwayWIEA

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Histidine metabolism (00340)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tyrosine metabolism (00350)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tryptophan metabolism (00380)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Alkaloid biosynthesis I (00950)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Phenylalanine metabolism (00360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway