IpiRecord: IPI00026102

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C	IEA	IDA IDA IDA IDA	ISS IEA
extracellular region	C	NAS	IEA	IMP ISS IEA
interleukin-10 receptor binding	F	NAS		IDA ISS
cytokine activity	F	IEA	IDA IMP	ISS IEA
protein binding	F	IPI		IEA
B cell differentiation	P	NAS		ISS
leukocyte chemotaxis	P	TAS		ISS
immune response	P	IEA	IEA	IMP IEA
defense response to bacterium	P	IEA	IDA	ISS IEA
inflammatory response	P	NAS
regulation of sensory perception of pain	P			IDA
negative regulation of myeloid dendritic cell activation	P	IEA	IMP	IEA
response to glucocorticoid stimulus	P			IEP
negative regulation of tumor necrosis factor biosynthetic process	P			IDA
negative regulation of interferon-alpha biosynthetic process	P	NAS		ISS
B cell proliferation	P	NAS		ISS
anti-apoptosis	P	NAS		ISS
negative regulation of T cell proliferation	P	NAS		ISS
cytoplasmic sequestering of NF-kappaB	P	NAS		ISS
positive regulation of MHC class II biosynthetic process	P	IEA	IDA	ISS IEA
negative regulation of MHC class II biosynthetic process	P	TAS		ISS
hemopoiesis	P	TAS		ISS
cell-cell signaling	P	IC		ISS
response to molecule of bacterial origin	P	IDA
regulation of isotype switching	P	NAS		ISS
negative regulation of nitric oxide biosynthetic process	P			IDA
response to stress	P			IEP
T-helper 2 type immune response	P	TAS		ISS
negative regulation of interleukin-12 production	P	IEA	IMP	IEA
negative regulation of cytokine production	P			IMP

Cellular Component

Biological Process

Molecular Function

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
endocrine/exocrine gland phenotype	MP		Un
immune system phenotype	MP		Un Un Un Un
tumorigenesis	MP		Un
normal phenotype	MP		Un Un
digestive/alimentary phenotype	MP		Un Un Un
hematopoietic system phenotype	MP		Un
liver/biliary system phenotype	MP		Un
growth/size phenotype	MP		Un
life span-post-weaning/aging	MP		Un Un Un

Disease (26)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Vasculitis	D			ISS
Rheumatic Heart Disease	D			ISS
??	D			ISS
Wegener's Granulomatosis	D			ISS
Stress	D			IEP
Pericardial Effusion	D			ISS
Carotid Artery Diseases	D			ISS
Sjogren's Syndrome	D			ISS
Myocardial Infarction	D			ISS
Neuralgia	D			IED
Carotid Stenosis	D			ISS
Arteriosclerosis	D			ISSISS
Venous Thrombosis	D			ISS
Behcet's Syndrome	D			ISS
Cerebrovascular Accident	D			ISSISS
Shock, Septic	D			ISS
Mitral Valve Stenosis	D			ISS
Myocarditis	D			IED
Coronary Arteriosclerosis	D			ISS
Diabetic Retinopathy	D			ISS
Wounds and Injuries	D			IEP
Heart Failure, Congestive	D			IEP
Thrombosis	D			ISS
Neoplasm Metastasis	D			ISS
Reperfusion Injury	D			ISS
Lupus Erythematosus, Systemic	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
Interleukin-10 signaling pathway	W			ISS

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway