IpiRecord: IPI00026262

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
ruffle	C		IDA	IEA
plasma membrane	C		IDA	IEA
intracellular	C	IEA		IEA
cytoplasm	C			ISS
receptor binding	F			ISS IEA
protein binding	F		IPI IPI	ISS
potassium channel inhibitor activity	F			ISS
GTPase binding	F			ISS IEA
Ras GTPase activator activity	F			ISS
GTPase activator activity	F	IEA		IEA
negative regulation of cell adhesion	P			ISS ISS
embryonic development	P		IMP	ISS
negative regulation of neuron apoptosis	P		IMP	ISS
regulation of actin filament polymerization	P			ISS ISS
intracellular signaling cascade	P	IEA	RCA	ISS ISS IEA
regulation of small GTPase mediated signal transduction	P	IEA		IEA
actin cytoskeleton organization and biogenesis	P			NAS
cytokinesis	P			ISS
negative regulation of cell-matrix adhesion	P			ISS ISS
cell adhesion	P			NAS
positive regulation of anti-apoptosis	P			ISS ISS
regulation of RNA metabolic process	P			ISS
vasculogenesis	P		IMP	ISS
regulation of cell shape	P			ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
craniofacial phenotype	MP		Un
embryogenesis phenotype	MP		Un Un
lethality-embryonic/perinatal	MP		Un Un
nervous system phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un
limbs/digits/tail phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un
growth/size phenotype	MP		Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Arteriovenous Malformations	D			ISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
mitogen activated protein kinase signaling pathway	W			IEA
Huntington disease pathway	W			IEA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Huntington's disease (05040)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Axon guidance (04360)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway