IpiRecord: IPI00026288

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C			ISS
neuron projection	C			IDA
integral to plasma membrane	C	IC		ISS
membrane	C	IEA		IEA
integral to membrane	C			ISS IEA
nucleotide binding	F	IEA		IEA
receptor activity	F	IEA		IEA
insulin-like growth factor binding	F	IDA IDA		TAS ISS ISS ISS
transferase activity	F	IEA		IEA
phosphoinositide 3-kinase binding	F	IPI		ISS ISS
insulin-like growth factor receptor activity	F	IDA		TAS ISS ISS
protein binding	F			ISS
ATP binding	F	IEA		IEA
protein serine/threonine kinase activity	F			ISS
insulin receptor substrate binding	F	IPI		ISS IPI ISS
axonogenesis	P			IMP
regulation of progression through cell cycle	P	TAS		ISS
protein amino acid autophosphorylation	P	IDA IDA IDA		ISS ISS
establishment of cell polarity	P			IMP
positive regulation of cell proliferation	P	TAS		ISS
neurite development	P			IDA
insulin-like growth factor receptor signaling pathway	P	IDA		ISS ISS ISS
anti-apoptosis	P	TAS		ISS
signal transduction	P	TAS		ISS
insulin receptor signaling pathway	P	TAS		ISS
organ morphogenesis	P	IEA		ISS IEA
protein tetramerization	P	IDA		ISS ISS
brain development	P	IEA		ISS ISS IEA
male sex determination	P	IEA		ISS IEA
protein heterooligomerization	P			IDA

Cellular Component

Biological Process

Molecular Function

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Fetal Growth Retardation	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
insulin-like growth factor signaling pathway	W			IMPISS

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Long-term depression (04730)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Adherens junction (04520)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway