IpiRecord: IPI00026407

IPI00026407 - FGF23, FIBROBLAST GROWTH FACTOR 23 PRECURSOR.
Uniprot Accession: Q7Z4T2
Uniprot ID: Q7Z4T2_HUMAN
Mapping: Chr 12, 4347654 - 4359155
Entrez Gene: 8074
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4898)
Rat: Fgf23, FIBROBLAST GROWTH FACTOR 23 PRECURSOR.
Mouse: Fgf23, FIBROBLAST GROWTH FACTOR 23 PRECURSOR.
Human: FGF23, FIBROBLAST GROWTH FACTOR 23 PRECURSOR.

Annotations for FGF23 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCNAS RCA ISS 
extracellular region partCIDA 
growth factor activityFIEA TAS ISS ISS IEA 
fibroblast growth factor receptor bindingFTAS ISS TAS 
phosphate transmembrane transporter activityFISS 
regulation of bone mineralizationPIEA IMP ISS IEA 
vitamin D metabolic processPIEP 
cell differentiationPNAS 
cellular phosphate ion homeostasisPIEA IMP ISS ISS IEA 
phosphate metabolic processPIEP 
phosphate transportPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn Un Un
immune system phenotypeMPUn
skeleton phenotypeMPUn Un Un
renal/urinary system phenotypeMPUn
limbs/digits/tail phenotypeMPUn Un Un
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn
growth/size phenotypeMPUn Un Un
life span-post-weaning/agingMPUn Un Un

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hypophosphatemia, FamilialDISS
RicketsDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
MAPK signaling pathway (04010)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway