IPI report for IPI00026904

IPI00026904 - ADSL, ISOFORM 1 OF ADENYLOSUCCINATE LYASE.
Uniprot Accession: Q71UA4
Uniprot ID: Q71UA4_HUMAN
Mapping: Chr 22, 39072466 - 39092929
Entrez Gene: 158
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P30566-1 UniProtKB/Swiss-Prot: PUR8_HUMAN Vega: OTTHUMP00000028724 REFSEQ_REVIEWED: NP_000017 REFSEQ_REVIEWED: GI:4557269 UniProtKB/TrEMBL: Q71UA4 UniProtKB/TrEMBL: Q71UA4_HUMAN ENSEMBL: ENSP00000216194 ENSEMBL: ENSG00000100357 H-InvDB: HIT000279081 UniParc: UPI0000132AC7 HGNC: 291 Entrez Gene: 158 UniGene: Hs.75527 CCDS: CCDS14001.1 EPD: EP74474 UTRdb: BB003393 UTRdb: BB046595 UTRdb: BB046596 UTRdb: BB056599 UTRdb: BB073200 UTRdb: BB101344 UTRdb: BB348488 RZPD: Hs.75527 InterPro: IPR000362 InterPro: IPR008948 InterPro: IPR004769 Pfam: PF00206 PRINTS: PR00149 TIGRFAMs: TIGR00928 PROSITE: PS00163 SUPERFAMILY: SSF48557

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7208)
Rat: Adsl_predicted, SIMILAR TO ADENYLOSUCCINATE LYASE.
Mouse: Adsl, CLONE:G730029K06 PRODUCT:ADENYLOSUCCINATE LYASE, FULL INSERT SEQUENCE.
Mouse: Adsl, ADENYLOSUCCINATE LYASE.
Human: ADSL, ISOFORM 1 OF ADENYLOSUCCINATE LYASE.
Human: ADSL, ISOFORM 2 OF ADENYLOSUCCINATE LYASE.

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Mouse	Rat
soluble fraction	C		IDA
catalytic activity	F	IEA
adenylosuccinate lyase activity	F	ISS	ISS IDA IMP IDA
lyase activity	F	IEA
response to hypoxia	P		IEP
purine ribonucleotide biosynthetic process	P	IEA
response to nutrient	P		IDA
purine nucleotide metabolic process	P		IDA IDA IMP
aerobic respiration	P		IMP
purine nucleotide biosynthetic process	P	IEA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Rat
Breast Neoplasms	D	IEP
Liver Neoplasms, Experimental	D	IEP
Diabetes Mellitus, Experimental	D	IEP
Prostatic Neoplasms	D	ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Purine metabolism (00230)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway
Alanine and aspartate metabolism (00252)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway

IpiRecord: IPI00026904

Annotations for ADSL and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

Cellular Component

Biological Process

Molecular Function

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)