IpiRecord: IPI00027174

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
integral to plasma membrane	C			ISS
membrane	C		IEA
lysosome	C		IDA	ISS
perinuclear region of cytoplasm	C		IDA	ISS
internal side of plasma membrane	C		IDA	ISS
integral to membrane	C	IEA	RCA	ISS
cellular_component	C			ND
ATP binding	F	IEA	IEA IEA	IEA
receptor activity	F	IEA	IEA	IEA
protein-tyrosine kinase activity	F	IEA	IEA IEA	IEA
nucleotide binding	F	IEA	IEA
kinase activity	F		IEA
identical protein binding	F			ISS
protein kinase activity	F		IEA
fibroblast growth factor receptor activity	F		IDA	ISS ISS NAS
growth factor activity	F			NAS
transferase activity	F	IEA	IEA
positive regulation of MAPKKK cascade	P		ISS
inner ear development	P		IMP
positive regulation of peptidyl-tyrosine phosphorylation	P		IDA	ISS
morphogenesis of an epithelium	P		IMP
cell-cell signaling	P			IDA
protein amino acid phosphorylation	P	IEA	IEA	IEA
MAPKKK cascade	P		IDA	ISS ISS
negative regulation of cell proliferation	P		IMP	ISS
inner ear receptor cell differentiation	P		IMP
forebrain development	P		IMP	ISS
positive regulation of apoptosis	P		IMP	ISS
cell growth	P			ISS
JAK-STAT cascade	P			ISS
skeletal development	P			ISS
positive regulation of protein ubiquitination	P		IDA
negative regulation of epithelial cell proliferation	P		IMP ISS
positive regulation of cell differentiation	P		IMP IMP	ISS
fibroblast growth factor receptor signaling pathway	P		IDA	ISS ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (20)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
craniofacial phenotype	MP		Un Un Un Un Un Un
homeostasis/metabolism phenotype	MP		Un
behavior/neurological phenotype	MP		Un Un
immune system phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un Un
lethality-postnatal	MP		Un Un
skeleton phenotype	MP		Un Un Un Un Un Un Un Un
life span-post-weaning/aging	MP		Un Un Un
nervous system phenotype	MP		Un
growth/size phenotype	MP		Un Un Un Un Un Un Un
normal phenotype	MP		Un
limbs/digits/tail phenotype	MP		Un Un Un Un Un Un Un Un
hematopoietic system phenotype	MP		Un
reproductive system phenotype	MP		Un Un
hearing/vestibular/ear phenotype	MP		Un
respiratory system phenotype	MP		Un Un
kyphosis	N			IEA
abnormal skeleton development	N			IEA
scoliosis	N			IEA

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Achondroplasia	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway