IpiRecord: IPI00027481

IPI00027481 - ABCB1, MULTIDRUG RESISTANCE PROTEIN 1.
Uniprot Accession: Q59GY9
Uniprot ID: Q59GY9_HUMAN
Mapping: Chr 7, 86970884 - 87180500
Entrez Gene: 5243
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4303)
Rat: Abcb1a, MULTIDRUG RESISTANCE PROTEIN 1A.
Mouse: Abcb1a, MULTIDRUG RESISTANCE PROTEIN 3.
Mouse: Abcb1a, ATP-BINDING CASSETTE, SUB-FAMILY B (MDR/TAP), MEMBER 1A.
Rat: Abcb1a, 137 KDA PROTEIN.
Human: ABCB1, MULTIDRUG RESISTANCE PROTEIN 1.
Human: ABCB1, P-GLYCOPROTEIN 1.

Annotations for ABCB1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
intercellular canaliculusCIDA 
integral to membraneCTAS IEA RCA IEA 
membraneCIEA IEA 
membrane fractionCTAS 
cell surfaceCIEP 
ATPase activityFIEA IEA IEA 
ATPase activity, coupledFIDA 
nucleotide bindingFIEA IEA IEA IEA 
nucleoside-triphosphatase activityFIEA 
transporter activityFTAS 
molecular_functionFND 
ATP bindingFTAS IEA IEA IEA IEA 
hydrolase activityFIEA IEA 
ATPase activity, coupled to transmembrane movement of substancesFIEA IEA IEA 
protein bindingFIPI 
xenobiotic-transporting ATPase activityFIEA IEA 
transportPTAS IEA IEA IEA IEA 
drug transportPIDA 
response to drugPTAS IEP 
response to cadmium ionPIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMP#
homeostasis/metabolism phenotypeMP##
immune system phenotypeMP#
cardiovascular system phenotypeMP#
hematopoietic system phenotypeMP#
reproductive system phenotypeMP#
hearing/vestibular/ear phenotypeMP#

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Kidney Failure, ChronicDIEP
Crohn DiseaseDISS
Colitis, UlcerativeDISS
Status EpilepticusDIEP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ABC transporters - General (02010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway