IpiRecord: IPI00027847

IPI00027847 - LPL, LIPOPROTEIN LIPASE PRECURSOR.
Uniprot Accession: Q8NEW3
Uniprot ID: Q8NEW3_HUMAN
Mapping: Chr 8, 19841232 - 19867912
Entrez Gene: 4023
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12726)
Rat: Lpl, LIPOPROTEIN LIPASE PRECURSOR.
Mouse: Lpl, LIPOPROTEIN LIPASE PRECURSOR.
Mouse: Lpl, LIPOPROTEIN LIPASE.
Human: LPL, LIPOPROTEIN LIPASE PRECURSOR.

Annotations for LPL and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
membraneCIEA IEA IEA 
extracellular spaceCRCA ISS 
extracellular matrixCIDA 
extracellular regionCTAS ISS 
chylomicronCIEA IEA IEA 
hydrolase activityFIEA IEA IEA 
GPI anchor bindingFIEA IEA IEA 
triglyceride bindingFIDA 
lipoprotein lipase activityFTAS IDA IDA ISS IDA IEA 
heparin bindingFTAS IEA ISS IEA 
lipid transporter activityFIEA IEA IEA 
catalytic activityFIEA 
fatty acid metabolic processPNR ISS 
lipid metabolic processPIEA 
lipid catabolic processPIEA IEA IDA IEA 
triacylglycerol biosynthetic processPIMP 
circulationPTAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (15)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
adipose tissue phenotypeMPUn
liver/biliary system phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un Un
lethality-embryonic/perinatalMPUn Un
muscle phenotypeMPUn Un
life span-post-weaning/agingMPUn
cardiovascular system phenotypeMPUn Un Un
respiratory system phenotypeMPUn Un
increased circulating free fatty acid levelNISS
muscular atrophyNISS
premature deathNISS
decreased circulating triglyceride levelNISS
weight lossNISS
myopathyNISS

Disease (5)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
HypertriglyceridemiaDISS
Diabetes Mellitus, Non-Insulin-DependentDISS
Lipoprotein Lipase Deficiency, FamilialDISS
Coronary ArteriosclerosisDISS
HypertensionDISS

Pathway (4)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
lipid metabolic pathwayWISS
glycerolipid metabolic pathwayWIEA
Alzheimer disease pathwayWIEA
lipoprotein metabolic pathwayWISS

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
PPAR signaling pathway (03320)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Glycerolipid metabolism (00561)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway