IpiRecord: IPI00028076

IPI00028076 - VEGFC, VASCULAR ENDOTHELIAL GROWTH FACTOR C PRECURSOR.
Uniprot Accession: Q6FH59
Uniprot ID: Q6FH59_HUMAN
Mapping: Chr 4, 177841685 - 177950889
Entrez Gene: 7424
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12813)
Rat: Vegfc, VASCULAR ENDOTHELIAL GROWTH FACTOR C PRECURSOR.
Mouse: Vegfc, VASCULAR ENDOTHELIAL GROWTH FACTOR C PRECURSOR.
Human: VEGFC, VASCULAR ENDOTHELIAL GROWTH FACTOR C PRECURSOR.

Annotations for VEGFC and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCRCA IDA ISS 
membraneCIEA IEA IEA 
vascular endothelial growth factor receptor 3 bindingFIPI IPI IMP 
growth factor activityFIEA IEA IEA TAS IEA 
positive regulation of protein amino acid autophosphorylationPIMP 
morphogenesis of embryonic epitheliumPIEA IMP ISS IEA 
positive regulation of epithelial cell proliferationPIMP 
positive regulation of blood vessel endothelial cell migrationPIMP 
positive regulation of neuroblast proliferationPISS IDA 
positive regulation of protein secretionPIMP 
regulation of progression through cell cyclePIEA IEA IEA 
positive regulation of cell proliferationPTAS ISS IMP IGI ISS ISS 
cell differentiationPIEA IEA IEA 
cell proliferationPIEA IEA IEA 
lymphangiogenesisPISS 
organ morphogenesisPIEA IMP ISS IEA 
signal transductionPTAS ISS 
substrate-bound cell migrationPTAS ISS 
angiogenesisPIEA IEA IMP IEA 
vascular endothelial growth factor receptor signaling pathwayPIDA IGI 
regulation of angiogenesisPTAS 
multicellular organismal developmentPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
lethality-embryonic/perinatalMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
vascular endothelial growth factor signaling pathwayWIMP

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
mTOR signaling pathway (04150)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway