IpiRecord: IPI00028570

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytosol	C		IDA	ISS ISS IEA
cytoplasm	C		ISS	TAS
nucleus	C		IDA ISS	ISS ISS IEA
nucleotide binding	F		IEA	IEA
p53 binding	F		ISS
kinase activity	F		IEA
protein binding	F		IPI	IDA ISS ISS
glycogen synthase kinase 3 activity	F		ISS ISS	TAS IDA ISS
protein kinase activity	F		IDA	ISS
ATP binding	F		IEA IEA	IEA
protein serine/threonine kinase activity	F		IEA IEA	IEA
NF-kappaB binding	F			ISS
tau-protein kinase activity	F		IDA	ISS IEA
transferase activity	F		IEA	IEA
protein kinase binding	F			IPI
beta-catenin binding	F		IPI	ISS IEA
negative regulation of transcription, DNA-dependent	P			IDA
intracellular signaling cascade	P		ISS
protein export from nucleus	P		IDA	ISS IEA
peptidyl-serine phosphorylation	P		ISS
fat cell differentiation	P		IDA	ISS IEA
establishment and/or maintenance of cell polarity	P			IDA
cell proliferation	P		TAS	ISS
protein amino acid phosphorylation	P		IDA IDA IDA	ISS IEA
Wnt receptor signaling pathway	P		IGI	IEA
response to stress	P		IDA	ISS IEA
induction of apoptosis	P			IDA TAS
glycogen metabolic process	P			ISS
establishment of cell polarity	P			IDA
ER overload response	P		ISS IDA
negative regulation of apoptosis	P		ISS
re-entry into mitotic cell cycle	P		IDA	ISS IEA
anti-apoptosis	P		IMP	ISS IEA
organ morphogenesis	P		IMP	ISS IEA
positive regulation of protein export from nucleus	P		ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
craniofacial phenotype	MP		Un Un
behavior/neurological phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
liver/biliary system phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un Un
skeleton phenotype	MP		Un Un
digestive/alimentary phenotype	MP		Un Un
normal phenotype	MP		Un
lethality-postnatal	MP		Un
embryonic lethality	N			ISS
neurodegeneration	N			ISSIED
liver degeneration	N			ISS

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
??	B			ISSISSISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
long term depression	W			IMP
canonical Wnt signaling pathway	W			IDA
Alzheimer disease pathway	W			IEA

KEGG Pathway (9)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Alzheimer's disease (05010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Hedgehog signaling pathway (04340)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
B cell receptor signaling pathway (04662)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cell cycle (04110)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Wnt signaling pathway (04310)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Axon guidance (04360)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway