IpiRecord: IPI00029104

IPI00029104 - GADD45A, GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA.
Uniprot Accession: Q5TCA8
Uniprot ID: Q5TCA8_HUMAN
Mapping: Chr 1, 67923332 - 67926609
Entrez Gene: 1647
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4643)
Rat: Gadd45a, GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA.
Mouse: Gadd45a, GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA.
Rat: Gadd45a, GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE 45 ALPHA.
Human: GADD45A, GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA.
Human: GADD45A, GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE, ALPHA.

Annotations for GADD45A and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCTAS TAS ISS ISS 
protein bindingFIPI ISS IEA 
apoptosisPTAS ISS 
regulation of progression through cell cyclePIDA ISS IEA 
negative regulation of protein kinase activityPIDA ISS IEA 
cell cycle arrestPTAS IEA ISS IEA 
DNA repairPTAS ISS 
cell cyclePIEA IEA IEA 
regulation of cyclin-dependent protein kinase activityPTAS ISS 
centrosome cyclePIGI ISS IEA 
response to DNA damage stimulusPIEA TAS IEA 
G2/M transition of mitotic cell cyclePIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
cellular phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
renal/urinary system phenotypeMPUn
nervous system phenotypeMPUn
tumorigenesisMPUn
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway