IpiRecord: IPI00029151

IPI00029151 - IL21, INTERLEUKIN 21.
Uniprot Accession: A5J0L4
Uniprot ID: A5J0L4_HUMAN
Mapping: Chr 4, 123753221 - 123761662
Entrez Gene: 59067
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2340)
Rat: Il21_predicted, INTERLEUKIN 21.
Mouse: Il21, INTERLEUKIN-21 ISOFORM.
Human: IL21, INTERLEUKIN 21.

Annotations for IL21 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCNAS RCA ISS ISS 
interleukin-2 receptor bindingFIPI ISS 
cytokine activityFIEA 
hematopoietin/interferon-class (D200-domain) cytokine receptor bindingFIDA ISS 
cell maturationPIDA ISS 
positive regulation of interferon-gamma biosynthetic processPNAS ISS 
signal transductionPNAS ISS 
positive regulation of T cell proliferationPIDA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn
normal phenotypeMPUn
hematopoietic system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Jak-STAT signaling pathway (04630)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway