| IPI00029772 - DPYD, DIHYDROPYRIMIDINE DEHYDROGENASE [NADP+] PRECURSOR. | |
|---|---|
| Uniprot Accession: Q5VXW9 | |
| Uniprot ID: Q5VXW9_HUMAN | |
| Mapping: Chr 1, 97315887 - 98159193 | |
| Entrez Gene: 1806 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2803) |
|---|
| Rat: Dpyd, DIHYDROPYRIMIDINE DEHYDROGENASE. |
| Mouse: Dpyd, DIHYDROPYRIMIDINE DEHYDROGENASE. |
| Human: DPYD, DIHYDROPYRIMIDINE DEHYDROGENASE [NADP+] PRECURSOR. |
| Human: DPYD, DPYD PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| soluble fraction | C | IDA | ||
| cytoplasm | C | NAS | ISS IEA | |
| membrane | C | IEA | ||
| cytosol | C | IDA | ISS IDA | |
| FAD binding | F | IEA | IEA | |
| iron-sulfur cluster binding | F | IEA | IEA | |
| metal ion binding | F | IEA | IEA | IEA |
| dihydroorotate oxidase activity | F | IEA | IEA | |
| electron carrier activity | F | IEA | RCA | ISS IEA |
| iron ion binding | F | IEA | IEA | IEA |
| NADP binding | F | IDA | ||
| dihydroorotate dehydrogenase activity | F | IEA | IEA | |
| uracil binding | F | IDA | ||
| dihydropyrimidine dehydrogenase (NADP+) activity | F | NAS | IDA | IDA ISS ISS IEA IDA |
| oxidoreductase activity | F | IEA | ||
| 4 iron, 4 sulfur cluster binding | F | IEA | IEA | IEA |
| metabolic process | P | IEA | IEA | |
| response to nutrient | P | IDA | ||
| pyrimidine base catabolic process | P | IDA | TAS ISS IDA | |
| thymidine catabolic process | P | NAS | ISS | |
| 'de novo' pyrimidine base biosynthetic process | P | IEA | IEA | |
| circadian rhythm | P | IDA | ||
| response to glucocorticoid stimulus | P | IEP | ||
| uracil metabolic process | P | IDA | ||
| uracil catabolic process | P | NAS | ISS | |
| response to drug | P | IDA | ||
| electron transport | P | IEA | RCA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Liver Diseases | D | IEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| pantothenate and CoA biosynthetic pathway | W | IEA | ||
| beta-alanine metabolic pathway | W | IEA | ||
| pyrimidine metabolic pathway | W | IEA IDA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| beta-Alanine metabolism (00410) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pyrimidine metabolism (00240) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pantothenate and CoA biosynthesis (00770) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |