IpiRecord: IPI00033008

IPI00033008 - FOS, PROTO-ONCOGENE PROTEIN C-FOS.
Uniprot Accession: Q76MZ0
Uniprot ID: Q76MZ0_HUMAN
Mapping: Chr 14, 74815284 - 74818685
Entrez Gene: 2353
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6481)
Rat: Fos, PROTO-ONCOGENE PROTEIN C-FOS.
Mouse: Fos, PROTO-ONCOGENE PROTEIN C-FOS.
Human: FOS, PROTO-ONCOGENE PROTEIN C-FOS.

Annotations for FOS and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCTAS IDA IC IDA ISS TAS ISS ISS IEA 
transcription factor complexCIEA IDA ISS IEA 
protein heterodimerization activityFIDA 
double-stranded DNA bindingFIDA 
transcription factor activityFIEA IDA IMP TAS ISS IEA 
sequence-specific DNA bindingFIEA IEA IEA 
protein dimerization activityFIEA IEA 
DNA bindingFIDA IDA ISS 
specific RNA polymerase II transcription factor activityFTAS ISS 
cellular processPIEA 
regulation of progression through cell cyclePIEA 
DNA methylationPTAS ISS 
inflammatory responsePTAS ISS 
nervous system developmentPIEA IMP ISS IEA 
regulation of transcription, DNA-dependentPIDA IMP ISS IEA 
regulation of transcription from RNA polymerase II promoterPTAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (23)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn Un
life span-post-weaning/agingMPUn
behavior/neurological phenotypeMPUn Un Un
endocrine/exocrine gland phenotypeMPUn
growth/size phenotypeMPUn Un
other phenotypeMPUn
immune system phenotypeMPUn Un
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
skeleton phenotypeMPUn Un
nervous system phenotypeMPUn Un
hematopoietic system phenotypeMPUn Un
tumorigenesisMPUn Un
hearing/vestibular/ear phenotypeMPUn
normal phenotypeMPUn
limbs/digits/tail phenotypeMPUn Un
reproductive system phenotypeMPUn
vision/eye phenotypeMPUn
impaired hematopoiesisNIEA
osteoporosisNIEA
abnormal bone remodelingNIEA
postnatal growth retardationNIEA
failure of tooth eruptionNIEA

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway