| IPI00059964 - APH1A, ISOFORM 1 OF GAMMA-SECRETASE SUBUNIT APH-1A. | |
|---|---|
| Uniprot Accession: Q5TB23 | |
| Uniprot ID: Q5TB23_HUMAN | |
| Mapping: Chr 1, 148504428 - 148508327 | |
| Entrez Gene: 51107 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2499) |
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| Rat: Aph1a, 29 KDA PROTEIN. |
| Mouse: Aph1a, ISOFORM 2 OF GAMMA-SECRETASE SUBUNIT APH-1A. |
| Mouse: Aph1a, ISOFORM 1 OF GAMMA-SECRETASE SUBUNIT APH-1A. |
| Rat: Aph1a, ANTERIOR PHARYNX DEFECTIVE 1A HOMOLOG. |
| Human: APH1A, ISOFORM 1 OF GAMMA-SECRETASE SUBUNIT APH-1A. |
| Human: APH1A, ANTERIOR PHARYNX DEFECTIVE 1 HOMOLOG A. |
| Human: APH1A, UNCHARACTERIZED PROTEIN APH1A. |
| Human: APH1A, ISOFORM 2 OF GAMMA-SECRETASE SUBUNIT APH-1A. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to membrane | C | IEA | ISS | IEA |
| Golgi apparatus | C | IEA | ||
| endoplasmic reticulum | C | IEA | ||
| membrane | C | IEA | ||
| protein binding | F | IEA | IEA | IEA |
| endopeptidase activity | F | IDA IMP | ISS | |
| peptidase activity | F | ISS | ||
| positive regulation of enzyme activity | P | IEA | IEA | IEA |
| metanephros development | P | IMP | ISS | |
| protein processing | P | IEA | ISS | IEA |
| Notch signaling pathway | P | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| skeleton phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| nervous system phenotype | MP | Un Un | ||
| normal phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un | ||
| growth/size phenotype | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Alzheimer's disease (05010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Notch signaling pathway (04330) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |