| IPI00073318 - CASP8, ISOFORM 7 OF CASPASE-8 PRECURSOR. | |
|---|---|
| Uniprot Accession: Q14790-7 | |
| Uniprot ID: CASP8_HUMAN | |
| Mapping: Chr 2, 201806426 - 201860677 | |
| Entrez Gene: 841 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8758) |
|---|
| Rat: Casp8, CASPASE-8. |
| Mouse: Casp8, CASPASE-8 PRECURSOR. |
| Rat: Casp8, 55 KDA PROTEIN. |
| Human: CASP8, ISOFORM 1 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, ISOFORM 7 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, ISOFORM 2 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, ISOFORM 3 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, ISOFORM 5 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, ISOFORM 6 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, CASP8 PROTEIN. |
| Human: CASP8, ISOFORM 9 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, ISOFORM 4 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, ISOFORM 8 OF CASPASE-8 PRECURSOR. |
| Human: CASP8, CASPASE 8 ISOFORM I (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IDA | ISS | |
| Noc1p-Noc2p complex | C | IMP | ISS | |
| mitochondrion | C | ISS | ||
| cytoskeleton | C | ISS | ||
| nucleus | C | IDA | ISS | |
| protein binding | F | IEA | IPI | IEA |
| hydrolase activity | F | IEA | ||
| signal transducer activity | F | ISS | ||
| cysteine-type peptidase activity | F | IEA | ISS IEA | |
| peptidase activity | F | IMP | ISS | |
| identical protein binding | F | ISS | ||
| caspase activity | F | IEA | IDA IDA IDA | IDA ISS ISS IEA |
| apoptosis | P | IDA IMP IDA | IMP ISS | |
| neural tube formation | P | IMP | ISS | |
| regulation of apoptosis | P | IEA | IEA | IEA |
| heart development | P | IMP | ISS | |
| angiogenesis | P | IMP | ISS | |
| positive regulation of I-kappaB kinase/NF-kappaB cascade | P | ISS | ||
| apoptotic program | P | ISS | ISS | |
| macrophage differentiation | P | IMP | ISS | |
| proteolysis | P | IEA | IEA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| immune system phenotype | MP | Un Un Un Un | ||
| embryogenesis phenotype | MP | Un Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un | ||
| muscle phenotype | MP | Un Un Un | ||
| renal/urinary system phenotype | MP | Un | ||
| nervous system phenotype | MP | Un Un Un | ||
| respiratory system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un Un | ||
| hematopoietic system phenotype | MP | Un Un Un Un Un | ||
| life span-post-weaning/aging | MP | Un | ||
| liver/biliary system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| programmed cell death pathway | W | IEA | ||
| mitogen activated protein kinase signaling pathway | W | IEA | ||
| Huntington disease pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Toll-like receptor signaling pathway (04620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Huntington's disease (05040) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Dentatorubropallidoluysian atrophy (DRPLA) (05050) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Neurodegenerative Disorders (01510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |