IpiRecord: IPI00102107

IPI00102107 - NSD1, LYSINE-20 SPECIFIC.
Uniprot Accession: Q96L73-1
Uniprot ID: NSD1_HUMAN
Mapping: Chr 5, 176446493 - 176457726
Entrez Gene: 64324
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13047)
Rat: Fgfr4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 PRECURSOR.
Mouse: Fgfr4, ISOFORM 2 OF FIBROBLAST GROWTH FACTOR RECEPTOR 4 PRECURSOR.
Mouse: Fgfr4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 SPLICE VARIANT 17A (FRAGMENT).
Mouse: Fgfr4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 SPLICE VARIANT 17B (FRAGMENT).
Mouse: Fgfr4, ISOFORM 1 OF FIBROBLAST GROWTH FACTOR RECEPTOR 4 PRECURSOR.
Mouse: Fgfr4, FIBROBLAST GROWTH FACTOR RECEPTOR 4.
Rat: Fgfr4, 4 KDA PROTEIN.
Rat: Fgfr4, 83 KDA PROTEIN.
Rat: Fgfr4, 89 KDA PROTEIN.
Human: NSD1, LYSINE-20 SPECIFIC.
Human: FGFR4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 PRECURSOR.
Human: FGFR4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 ISOFORM 2 PRECURSOR.
Human: FGFR4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 VARIANT (FRAGMENT).
Mouse: Nsd1, NSD1.
Mouse: Nsd1, NUCLEAR RECEPTOR-BINDING SET-DOMAIN PROTEIN 1.
Rat: Nsd1_predicted, SIMILAR TO NUCLEAR RECEPTOR BINDING SET DOMAIN PROTEIN 1 ISOFORM B.
Rat: Nsd1_predicted, 54 KDA PROTEIN.
Rat: Nsd1_predicted, 257 KDA PROTEIN.

Annotations for NSD1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
histone methyltransferase complexCIC 
nucleusCIC IEA 
membraneCIEA IEA IEA 
integral to membraneCIEA IEA ISS IEA 
cellular_componentCND 
extracellular spaceCRCA ISS 
integral to plasma membraneCTAS ISS 
ATP bindingFIEA IEA IEA IEA 
transcription corepressor activityFIDA 
protein-tyrosine kinase activityFIEA IEA IEA IEA 
nucleotide bindingFIEA IEA IEA 
estrogen receptor bindingFIPI 
chromatin bindingFIDA 
protein bindingFIPI IEA 
kinase activityFIEA 
histone-lysine N-methyltransferase activityFIEA 
metal ion bindingFIEA 
protein serine/threonine kinase activityFISS 
retinoid X receptor bindingFIPI 
androgen receptor bindingFISS 
histone lysine N-methyltransferase activity (H3-K36 specific)FIDA 
fibroblast growth factor receptor activityFTAS IEA ISS ISS 
histone methyltransferase activityFIDA 
histone lysine N-methyltransferase activity (H4-K20 specific)FIDA 
zinc ion bindingFIEA IEA IEA 
ligand-dependent nuclear receptor bindingFIPI 
molecular_functionFND 
receptor activityFIEA IEA IEA 
transferase activityFIEA IEA IEA 
thyroid hormone receptor bindingFIPI 
methyltransferase activityFIEA 
protein kinase activityFIEA 
transcription cofactor activityFIDA 
protein amino acid phosphorylationPIEA IEA IEA 
lung developmentPIMP ISS 
induction of an organPIMP ISS 
histone methylationPIDA 
chromatin modificationPIEA 
gastrulation (sensu Mammalia)PIMP 
signal transductionPIEA 
transcriptionPIEA 
biological_processPND 
negative regulation of transcription from RNA polymerase II promoterPIDA 
multicellular organismal developmentPIEA 
regulation of transcription, DNA-dependentPTAS 
fibroblast growth factor receptor signaling pathwayPTAS ISS 
positive regulation of transcription, DNA-dependentPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
respiratory system phenotypeMPUn
reproductive system phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Beckwith-Wiedemann SyndromeDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Lysine degradation (00310)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway