| IPI00102107 - NSD1, LYSINE-20 SPECIFIC. | |
|---|---|
| Uniprot Accession: Q96L73-1 | |
| Uniprot ID: NSD1_HUMAN | |
| Mapping: Chr 5, 176446493 - 176457726 | |
| Entrez Gene: 64324 | |
| Entrez MapView: |
|
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13047) |
|---|
| Rat: Fgfr4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 PRECURSOR. |
| Mouse: Fgfr4, ISOFORM 2 OF FIBROBLAST GROWTH FACTOR RECEPTOR 4 PRECURSOR. |
| Mouse: Fgfr4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 SPLICE VARIANT 17A (FRAGMENT). |
| Mouse: Fgfr4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 SPLICE VARIANT 17B (FRAGMENT). |
| Mouse: Fgfr4, ISOFORM 1 OF FIBROBLAST GROWTH FACTOR RECEPTOR 4 PRECURSOR. |
| Mouse: Fgfr4, FIBROBLAST GROWTH FACTOR RECEPTOR 4. |
| Rat: Fgfr4, 4 KDA PROTEIN. |
| Rat: Fgfr4, 83 KDA PROTEIN. |
| Rat: Fgfr4, 89 KDA PROTEIN. |
| Human: NSD1, LYSINE-20 SPECIFIC. |
| Human: FGFR4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 PRECURSOR. |
| Human: FGFR4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 ISOFORM 2 PRECURSOR. |
| Human: FGFR4, FIBROBLAST GROWTH FACTOR RECEPTOR 4 VARIANT (FRAGMENT). |
| Mouse: Nsd1, NSD1. |
| Mouse: Nsd1, NUCLEAR RECEPTOR-BINDING SET-DOMAIN PROTEIN 1. |
| Rat: Nsd1_predicted, SIMILAR TO NUCLEAR RECEPTOR BINDING SET DOMAIN PROTEIN 1 ISOFORM B. |
| Rat: Nsd1_predicted, 54 KDA PROTEIN. |
| Rat: Nsd1_predicted, 257 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| histone methyltransferase complex | C | IC | ||
| nucleus | C | IC | IEA | |
| membrane | C | IEA | IEA | IEA |
| integral to membrane | C | IEA | IEA | ISS IEA |
| cellular_component | C | ND | ||
| extracellular space | C | RCA | ISS | |
| integral to plasma membrane | C | TAS | ISS | |
| ATP binding | F | IEA | IEA IEA | IEA |
| transcription corepressor activity | F | IDA | ||
| protein-tyrosine kinase activity | F | IEA | IEA IEA | IEA |
| nucleotide binding | F | IEA | IEA | IEA |
| estrogen receptor binding | F | IPI | ||
| chromatin binding | F | IDA | ||
| protein binding | F | IPI | IEA | |
| kinase activity | F | IEA | ||
| histone-lysine N-methyltransferase activity | F | IEA | ||
| metal ion binding | F | IEA | ||
| protein serine/threonine kinase activity | F | ISS | ||
| retinoid X receptor binding | F | IPI | ||
| androgen receptor binding | F | ISS | ||
| histone lysine N-methyltransferase activity (H3-K36 specific) | F | IDA | ||
| fibroblast growth factor receptor activity | F | TAS | IEA | ISS ISS |
| histone methyltransferase activity | F | IDA | ||
| histone lysine N-methyltransferase activity (H4-K20 specific) | F | IDA | ||
| zinc ion binding | F | IEA IEA | IEA | |
| ligand-dependent nuclear receptor binding | F | IPI | ||
| molecular_function | F | ND | ||
| receptor activity | F | IEA | IEA | IEA |
| transferase activity | F | IEA | IEA | IEA |
| thyroid hormone receptor binding | F | IPI | ||
| methyltransferase activity | F | IEA | ||
| protein kinase activity | F | IEA | ||
| transcription cofactor activity | F | IDA | ||
| protein amino acid phosphorylation | P | IEA | IEA | IEA |
| lung development | P | IMP | ISS | |
| induction of an organ | P | IMP | ISS | |
| histone methylation | P | IDA | ||
| chromatin modification | P | IEA | ||
| gastrulation (sensu Mammalia) | P | IMP | ||
| signal transduction | P | IEA | ||
| transcription | P | IEA | ||
| biological_process | P | ND | ||
| negative regulation of transcription from RNA polymerase II promoter | P | IDA | ||
| multicellular organismal development | P | IEA | ||
| regulation of transcription, DNA-dependent | P | TAS | ||
| fibroblast growth factor receptor signaling pathway | P | TAS | ISS | |
| positive regulation of transcription, DNA-dependent | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Beckwith-Wiedemann Syndrome | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Lysine degradation (00310) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |