IpiRecord: IPI00103662

IPI00103662 - VAV2, PP3781.
Uniprot Accession: Q8WY83
Uniprot ID: Q8WY83_HUMAN
Mapping: Chr 9, 135616837 - 135847547
Entrez Gene: 7410
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3131)
Rat: Vav2_predicted, SIMILAR TO PROTEIN VAV-2 ISOFORM 3.
Mouse: Vav2, VAV2 PROTEIN.
Mouse: Vav2, PROTEIN VAV-2.
Rat: Vav2_predicted, SIMILAR TO PROTEIN VAV-2 ISOFORM 1.
Rat: Vav2_predicted, SIMILAR TO PROTEIN VAV-2 ISOFORM 2.
Rat: Vav2_predicted, SIMILAR TO PROTEIN VAV-2 ISOFORM 4.
Human: VAV2, VAV 2 GUANINE NUCLEOTIDE EXCHANGE FACTOR.
Human: VAV2, PP3781.
Human: VAV2, CDNA FLJ26965 FIS, CLONE SLV01057.
Human: VAV2, UNCHARACTERIZED PROTEIN FLJ42277.
Human: VAV2, UNCHARACTERIZED PROTEIN VAV2.
Human: VAV2, PROTEIN VAV-2.
Human: VAV2, 97 KDA PROTEIN.

Annotations for VAV2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCIDA ISS 
intracellularCIEA IEA IEA 
cytoplasmCIDA ISS 
metal ion bindingFIEA IEA 
diacylglycerol bindingFIEA IEA 
guanyl-nucleotide exchange factor activityFIEA IMP ISS IEA 
protein bindingFIPI ISS 
Rho guanyl-nucleotide exchange factor activityFIEA IEA IEA 
epidermal growth factor receptor bindingFIPI ISS 
zinc ion bindingFIEA IEA 
positive regulation of phosphoinositide 3-kinase activityPIGI ISS 
small GTPase mediated signal transductionPIMP ISS 
cell projection biogenesisPIGI ISS 
intracellular signaling cascadePIEA IEA IEA 
regulation of Rho protein signal transductionPIEA IEA IEA 
cell migrationPIGI ISS 
lamellipodium biogenesisPIGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn
hematopoietic system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway