| IPI00104341 - EPHX2, EPOXIDE HYDROLASE 2. | |
|---|---|
| Uniprot Accession: P34913 | |
| Uniprot ID: HYES_HUMAN | |
| Mapping: Chr 8, 27404543 - 27458403 | |
| Entrez Gene: 2053 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12384) |
|---|
| Rat: Ephx2, EPOXIDE HYDROLASE 2. |
| Mouse: Ephx2, ISOFORM 1 OF EPOXIDE HYDROLASE 2. |
| Mouse: Ephx2, ISOFORM 2 OF EPOXIDE HYDROLASE 2. |
| Rat: Ephx2, 62 KDA PROTEIN. |
| Human: EPHX2, EPOXIDE HYDROLASE 2. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| peroxisome | C | IEA | IEA | TAS IDA IEA |
| cytosol | C | NAS | TAS ISS IDA IDA | |
| extracellular space | C | RCA | ISS | |
| cytoplasm | C | IEA | IEA | |
| soluble fraction | C | NAS | ISS | |
| protein homodimerization activity | F | NAS | ISS | |
| hydrolase activity | F | IEA | IEA IEA | IEA |
| metal ion binding | F | IEA | ||
| 4-nitrophenylphosphatase activity | F | IDA | ||
| catalytic activity | F | IEA | ||
| epoxide hydrolase activity | F | IDA | IDA ISS | |
| magnesium ion binding | F | IEA | IEA | IMP IEA |
| response to toxin | P | NAS | IEA | ISS IEA |
| aromatic compound catabolic process | P | IEA | IEA | IEA |
| cellular calcium ion homeostasis | P | NAS | ISS | |
| positive regulation of vasodilation | P | NAS | ISS | |
| inflammatory response | P | NAS | ISS IMP | |
| drug metabolic process | P | NAS | ISS | |
| metabolic process | P | IEA | IEA | IEA |
| linoleic acid metabolic process | P | IMP | ||
| blood pressure regulation | P | NAS | ISS | |
| prostaglandin production during acute inflammatory response | P | IMP | ||
| xenobiotic metabolic process | P | NAS | IEA | ISS IEA |
| positive regulation of blood pressure | P | IMP | ||
| sensory perception of pain | P | IMP | ||
| oxygen and reactive oxygen species metabolic process | P | NAS | ISS | |
| aromatic compound metabolic process | P | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Coronary Arteriosclerosis | D | ISS | ||
| Coronary Disease | D | ISS | ||
| Cerebral Infarction | D | IED | ||
| Hypertension | D | IED |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| tetrachloroethene degradation pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Arachidonic acid metabolism (00590) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Tetrachloroethene degradation (00625) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |