IpiRecord: IPI00104341

IPI00104341 - EPHX2, EPOXIDE HYDROLASE 2.
Uniprot Accession: P34913
Uniprot ID: HYES_HUMAN
Mapping: Chr 8, 27404543 - 27458403
Entrez Gene: 2053
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12384)
Rat: Ephx2, EPOXIDE HYDROLASE 2.
Mouse: Ephx2, ISOFORM 1 OF EPOXIDE HYDROLASE 2.
Mouse: Ephx2, ISOFORM 2 OF EPOXIDE HYDROLASE 2.
Rat: Ephx2, 62 KDA PROTEIN.
Human: EPHX2, EPOXIDE HYDROLASE 2.

Annotations for EPHX2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
peroxisomeCIEA IEA TAS IDA IEA 
cytosolCNAS TAS ISS IDA IDA 
extracellular spaceCRCA ISS 
cytoplasmCIEA IEA 
soluble fractionCNAS ISS 
protein homodimerization activityFNAS ISS 
hydrolase activityFIEA IEA IEA IEA 
metal ion bindingFIEA 
4-nitrophenylphosphatase activityFIDA 
catalytic activityFIEA 
epoxide hydrolase activityFIDA IDA ISS 
magnesium ion bindingFIEA IEA IMP IEA 
response to toxinPNAS IEA ISS IEA 
aromatic compound catabolic processPIEA IEA IEA 
cellular calcium ion homeostasisPNAS ISS 
positive regulation of vasodilationPNAS ISS 
inflammatory responsePNAS ISS IMP 
drug metabolic processPNAS ISS 
metabolic processPIEA IEA IEA 
linoleic acid metabolic processPIMP 
blood pressure regulationPNAS ISS 
prostaglandin production during acute inflammatory responsePIMP 
xenobiotic metabolic processPNAS IEA ISS IEA 
positive regulation of blood pressurePIMP 
sensory perception of painPIMP 
oxygen and reactive oxygen species metabolic processPNAS ISS 
aromatic compound metabolic processPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
cardiovascular system phenotypeMPUn

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Coronary ArteriosclerosisDISS
Coronary DiseaseDISS
Cerebral InfarctionDIED
HypertensionDIED

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
tetrachloroethene degradation pathwayWIEA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Arachidonic acid metabolism (00590)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tetrachloroethene degradation (00625)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway