| IPI00152350 - VWF, VWF PROTEIN. | |
|---|---|
| Uniprot Accession: Q8TCE8 | |
| Uniprot ID: Q8TCE8_HUMAN | |
| Mapping: Chr 12, 5928308 - 6104097 | |
| Entrez Gene: 7450 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5056) |
|---|
| Rat: Vwf, SIMILAR TO VON WILLEBRAND FACTOR. |
| Mouse: Vwf, INSERT SEQUENCE. |
| Mouse: Vwf, ISOFORM 1 OF VON WILLEBRAND FACTOR PRECURSOR. |
| Mouse: Vwf, SEQUENCE. |
| Rat: Vwf, SIMILAR TO VON WILLEBRAND FACTOR. |
| Rat: Vwf, 45 KDA PROTEIN. |
| Human: VWF, VON WILLEBRAND FACTOR PRECURSOR. |
| Human: VWF, VWF PROTEIN. |
| Human: VWF, 309 KDA PROTEIN. |
| Human: VWF, 8 KDA PROTEIN. |
| Human: VWF, 7 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular matrix | C | IDA | ||
| extracellular space | C | RCA | ISS | |
| platelet alpha granule | C | NAS | ||
| proteinaceous extracellular matrix | C | IEA | IEA IEA | IEA |
| extracellular region | C | NAS IDA | ||
| endoplasmic reticulum | C | IDA | ||
| molecular_function | F | ND | ||
| protein homodimerization activity | F | IDA | ||
| glycoprotein binding | F | IDA | ||
| integrin binding | F | IPI | ||
| protease binding | F | IPI | ISS | |
| chaperone binding | F | IDA | ||
| protein N-terminus binding | F | IPI | ||
| protein binding | F | IEA | IEA | |
| collagen binding | F | IDA | ||
| immunoglobulin binding | F | IDA | ||
| hemostasis | P | TAS IMP | ISS | |
| platelet activation | P | IDA NAS | IMP IMP | IMP IMP IEA |
| response to wounding | P | TAS | ||
| cell-substrate adhesion | P | IDA | IMP | |
| protein homooligomerization | P | IDA | ||
| cell adhesion | P | IEA | IEA IEA | IEA |
| response to stress | P | IEP | ||
| placenta development | P | IMP | IEA | |
| liver development | P | IMP | IEA | |
| tissue regeneration | P | NAS | ||
| blood coagulation | P | IEA | IMP IMP | ISS IMP IMP IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Obesity | D | ISSISS | ||
| Hypertension, Pulmonary | D | ISS | ||
| Metabolic Syndrome X | D | ISS | ||
| Purpura, Thrombocytopenic | D | ISS | ||
| Diabetes Mellitus, Experimental | D | IEP | ||
| Insulin Resistance | D | ISS | ||
| Behcet's Syndrome | D | ISS | ||
| Bernard-Soulier Syndrome | D | ISS | ||
| Diabetic Retinopathy | D | ISS | ||
| Coronary Disease | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| platelet aggregation pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| ECM-receptor interaction (04512) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cell Communication (01430) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Complement and coagulation cascades (04610) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |